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TitleStructural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.
Journal, issue, pagesNucleic Acids Res., Vol. 38, Page 7791-7799, Year 2010
Publish dateApr 27, 2010 (structure data deposition date)
AuthorsMacmaster, R. / Zelinskaya, N. / Savic, M. / Rankin, C.R. / Conn, G.L.
External linksNucleic Acids Res. / PubMed:20639535
MethodsX-ray diffraction
Resolution1.69 - 1.805 Å
Structure data

PDB-3mq2:
Crystal Structure of 16S rRNA Methyltranferase KamB
Method: X-RAY DIFFRACTION / Resolution: 1.69 Å

PDB-3mte:
Crystal Structure of 16S rRNA Methyltranferase
Method: X-RAY DIFFRACTION / Resolution: 1.805 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-HOH:
WATER

ChemComp-SAM:
S-ADENOSYLMETHIONINE

Source
  • streptomyces sp. dsm 40477 (bacteria)
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / Methyltranferase / Ribosomal / 16S / Antibiotic Resistance / Aminoglycoside / S-Adenosyl-L-Methionine / Methyltransferase / Resistance / RNA

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