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Structure paper

TitleThe crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model.
Journal, issue, pagesMol. Microbiol., Vol. 77, Page 456-470, Year 2010
Publish dateJan 21, 2010 (structure data deposition date)
AuthorsKotsyfakis, M. / Horka, H. / Salat, J. / Andersen, J.F.
External linksMol. Microbiol. / PubMed:20545851
MethodsX-ray diffraction
Resolution1.52 - 2.6762 Å
Structure data

PDB-3lh4:
Crystal Structure of Sialostatin L2
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3mwz:
Crystal structure of the selenomethionine derivative of the L 22,47,100 M mutant of sialostatin L2
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

PDB-4zm8:
Crystal Structure of Sialostatin L
Method: X-RAY DIFFRACTION / Resolution: 2.6762 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • ixodes scapularis (black-legged tick)
KeywordsHYDROLASE INHIBITOR / beta sheet / cystatin / Protease inhibitor / Thiol protease inhibitor / antiparallel beta-sheet / tick

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