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Structure paper

TitleGGA autoinhibition revisited
Journal, issue, pagesTraffic, Vol. 11, Page 259-273, Year 2010
Publish dateFeb 1, 2009 (structure data deposition date)
AuthorsCramer, J.F. / Gustafsen, C. / Behrens, M.A. / Oliveira, C.L.P. / Pedersen, J.S. / Madsen, P. / Petersen, C.M. / Thirup, S.S.
External linksTraffic / PubMed:20015111
MethodsX-ray diffraction
Resolution1.7 - 2.4 Å
Structure data

PDB-3g2s:
VHS Domain of human GGA1 complexed with SorLA C-terminal Peptide
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-3g2t:
VHS Domain of human GGA1 complexed with SorLA C-terminal Phosphopeptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3g2u:
VHS Domain of human GGA1 complexed with Sotilin C-terminal Peptide
Method: X-RAY DIFFRACTION / Resolution: 2.301 Å

PDB-3g2v:
VHS Domain of human GGA1 complexed with Sotilin C-terminal Phosphopeptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3g2w:
VHS Domain of human GGA1 complexed with a DXXLL hinge peptide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HEZ:
HEXANE-1,6-DIOL

ChemComp-HOH:
WATER

ChemComp-IOD:
IODIDE ION

Source
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT / ADP-ribosylation factor binding protein GGA1 / VHS / acidic-cluster dileucine signal / SorLA / Sortilin / Hinge domain / autoinhibition

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