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Structure paper

TitleA mycobacterial cyclic AMP phosphodiesterase that moonlights as a modifier of cell wall permeability
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 32846-32857, Year 2009
Publish dateJul 15, 2009 (structure data deposition date)
AuthorsPodobnik, M. / Tyagi, R. / Matange, N. / Dermol, U. / Gupta, A.K. / Mattoo, R. / Seshadri, K. / Visweswariah, S.S.
External linksJ. Biol. Chem. / PubMed:19801656
MethodsX-ray diffraction
Resolution1.6 - 1.8 Å
Structure data

PDB-3ib7:
Crystal structure of full length Rv0805
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-3ib8:
Crystal structure of full length Rv0805 in complex with 5'-AMP
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-FE:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-BTB:
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsHYDROLASE / metallophosphoesterase / alpha-beta fold / swapped-dimer

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