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Structure paper

TitleDesign of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.
Journal, issue, pagesCancer Res., Vol. 69, Page 7784-7792, Year 2009
Publish dateFeb 24, 2008 (structure data deposition date)
Authorsvan Stipdonk, M.J. / Badia-Martinez, D. / Sluijter, M. / Offringa, R. / van Hall, T. / Achour, A.
External linksCancer Res. / PubMed:19789338
MethodsX-ray diffraction
Resolution1.91 - 2.6 Å
Structure data

PDB-3cc5:
H-2Db complex with human gp100
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

PDB-3cch:
H-2Db complex with murine gp100
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3ch1:
Crystal structure of H-2Db in complex with chimeric gp100
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / murine MHC / Glycoprotein / Immune response / Membrane / MHC I / Transmembrane / Immunoglobulin domain / Secreted / Melanin biosynthesis / Disease mutation / MHC / H-2Db

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