+Search query
-Structure paper
Title | The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling. |
---|---|
Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 16, Page 691-697, Year 2009 |
Publish date | Jun 1, 2009 (structure data deposition date) |
Authors | Bosanac, I. / Maun, H.R. / Scales, S.J. / Wen, X. / Lingel, A. / Bazan, J.F. / de Sauvage, F.J. / Hymowitz, S.G. / Lazarus, R.A. |
External links | Nat. Struct. Mol. Biol. / PubMed:19561609 |
Methods | X-ray diffraction |
Resolution | 2.9 - 3.1 Å |
Structure data | PDB-3ho3: PDB-3ho4: PDB-3ho5: |
Chemicals | ChemComp-ZN: ChemComp-CA: |
Source |
|
Keywords | SIGNALING PROTEIN / receptor ectodomain / six-bladed-propeller domain / EGF domain / disulfide bond / Cell membrane / EGF-like domain / Glycoprotein / Membrane / Secreted / calcium cation / zinc cation / Autocatalytic cleavage / Developmental protein / Disease mutation / Holoprosencephaly / Hydrolase / Lipoprotein / Microphthalmia / Palmitate / Protease |