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Structure paper

TitleStructural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita
Journal, issue, pagesJ. Mol. Biol., Vol. 387, Page 694-705, Year 2009
Publish dateJan 23, 2008 (structure data deposition date)
AuthorsYang, N. / Li, D.F. / Feng, L. / Xiang, Y. / Liu, W. / Sun, H. / Wang, D.C.
External linksJ. Mol. Biol. / PubMed:19361423
MethodsX-ray diffraction
Resolution1.9 - 3 Å
Structure data

PDB-2zgk:
Crystal structure of wildtype AAL
Method: X-RAY DIFFRACTION / Resolution: 3.0 Å

PDB-2zgl:
Crystal structure of recombinant Agrocybe aegerita (rAAL)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2zgm:
Crystal structure of recombinant Agrocybe aegerita lectin,rAAL, complex with lactose
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2zgn:
crystal structure of recombinant Agrocybe aegerita lectin, rAAL, complex with galactose
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2zgo:
Crystal structure of AAL mutant H59Q complex with lactose
Method: X-RAY DIFFRACTION / Resolution: 2.0 Å

PDB-2zgp:
Crystal structure of Agrocybe aegerita lectin AAL mutant I25G
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-2zgq:
Crystal structure of AAL mutant L33A in P1 spacegroup
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2zgr:
Crystal structure of AAL mutant L33A in C2 spacegroup
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2zgs:
Crystal structure of Agrocybe aegerita lectin AAL mutant L47A
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2zgt:
Crystal structure of Agrocybe aegerita lectin AAL mutant F93G
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2zgu:
Crystal structure Agrocybe aegerita lectin AAL mutant I144G
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GAL:
beta-D-galactopyranose

Source
  • agrocybe aegerita (fungus)
KeywordsHYDROLASE / galectin / jelly roll / Apoptosis / Nuclease / jelly role

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