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Structure paper

TitleGermline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus.
Journal, issue, pagesEmbo J., Vol. 27, Page 2592-2602, Year 2008
Publish dateOct 20, 2008 (structure data deposition date)
AuthorsThomson, C.A. / Bryson, S. / McLean, G.R. / Creagh, A.L. / Pai, E.F. / Schrader, J.W.
External linksEmbo J. / PubMed:18772881
MethodsX-ray diffraction
Resolution2.3 - 2.95 Å
Structure data

PDB-3eyf:
Crystal structure of anti-human cytomegalovirus antibody 8f9 plus gB peptide
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3eyo:
Crystal structure of anti-human cytomegalovirus antibody 8F9
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3eyq:
Crystal structure of MJ5 Fab, a germline antibody variant of anti-human cytomegalovirus antibody 8f9
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3f12:
Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / cytomegalovirus / antibody / Immunoglobulin domain / Cleavage on pair of basic residues / Envelope protein / Glycoprotein / Host-virus interaction / Membrane / Transmembrane / Virion / Human cytomegalovirus / germline

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