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Structure paper

TitleStructural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Journal, issue, pagesEmbo J., Vol. 27, Page 804-816, Year 2008
Publish dateJan 3, 2008 (structure data deposition date)
AuthorsNg, C. / Jackson, R.A. / Buschdorf, J.P. / Sun, Q. / Guy, G.R. / Sivaraman, J.
External linksEmbo J. / PubMed:18273061
MethodsX-ray diffraction
Resolution1.35 - 2.6 Å
Structure data

PDB-3bum:
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3bun:
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty4
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3buo:
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in EGF receptor'
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3buw:
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Syk
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-3bux:
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in c-Met
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / signal transduction / proto-oncogene / complex / Cytoplasm / Developmental protein / Membrane / Microtubule / Polymorphism / Calcium / Metal-binding / Phosphoprotein / SH2 domain / Ubl conjugation pathway / Zinc / Zinc-finger / LIGASE/SIGNALING PROTEIN / Cbl / TKB / Alternative splicing / LIGASE-SIGNALING PROTEIN COMPLEX / Anti-oncogene / ATP-binding / Cell cycle / Disease mutation / Glycoprotein / Kinase / Nucleotide-binding / Receptor / Secreted / Transferase / Transmembrane / Tyrosine-protein kinase / Host-virus interaction / Ubl conjugation

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