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Structure paper

TitleStructure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Journal, issue, pagesMol. Cell, Vol. 28, Page 264-276, Year 2007
Publish dateJul 10, 2007 (structure data deposition date)
AuthorsNowotny, M. / Gaidamakov, S.A. / Ghirlando, R. / Cerritelli, S.M. / Crouch, R.J. / Yang, W.
External linksMol. Cell / PubMed:17964265
MethodsX-ray diffraction
Resolution2.4 - 3.2 Å
Structure data

PDB-2qk9:
Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-2qkb:
Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2qkk:
Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-16D:
HEXANE-1,6-DIAMINE

ChemComp-NA:
Unknown entry

ChemComp-FLC:
CITRATE ANION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-CA:
Unknown entry

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHYDROLASE/DNA/RNA / RNase H; RNA/DNA hybrid / HYDROLASE-DNA-RNA COMPLEX

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