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-Structure paper
Title | Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 5112-5117, Year 2006 |
Publish date | Jun 27, 2006 (structure data deposition date) |
Authors | Tully, D.C. / Liu, H. / Chatterjee, A.K. / Alper, P.B. / Epple, R. / Williams, J.A. / Roberts, M.J. / Woodmansee, D.H. / Masick, B.T. / Tumanut, C. ...Tully, D.C. / Liu, H. / Chatterjee, A.K. / Alper, P.B. / Epple, R. / Williams, J.A. / Roberts, M.J. / Woodmansee, D.H. / Masick, B.T. / Tumanut, C. / Li, J. / Spraggon, G. / Hornsby, M. / Chang, J. / Tuntland, T. / Hollenbeck, T. / Gordon, P. / Harris, J.L. / Karanewsky, D.S. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16876402 |
Methods | X-ray diffraction |
Resolution | 1.55 - 1.8 Å |
Structure data | PDB-2hh5: PDB-2hhn: |
Chemicals | ChemComp-ZN: ChemComp-CL: ChemComp-GNQ: ChemComp-HOH: ChemComp-SO4: |
Source |
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Keywords | HYDROLASE / Cathepsin S / noncovalent / inhibition / zinc / arylaminoethyl-amides / arylaminoethyl amide / protease |