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Structure paper

TitleThe 1.48 A Resolution Crystal Structure of the Homotetrameric Cytidine Deaminase from Mouse
Journal, issue, pagesBiochemistry, Vol. 45, Page 7825-7833, Year 2006
Publish dateApr 6, 2005 (structure data deposition date)
AuthorsTeh, A.H. / Kimura, M. / Yamamoto, M. / Tanaka, N. / Yamaguchi, I. / Kumasaka, T.
External linksBiochemistry / PubMed:16784234
MethodsX-ray diffraction
Resolution1.48 - 2.36 Å
Structure data

PDB-1zab:
Crystal Structure of Mouse Cytidine Deaminase Complexed with 3-Deazauridine
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

PDB-2fr5:
Crystal Structure of Mouse Cytidine Deaminase Complexed with Tetrahydrouridine
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

PDB-2fr6:
Crystal Structure of Mouse Cytidine Deaminase Complexed with Cytidine
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-URD:
1-((2R,3R,4S,5R)-TETRAHYDRO-3,4-DIHYDROXY-5-(HYDROXYMETHYL)FURAN-2-YL)PYRIDINE-2,4(1H,3H)-DIONE

ChemComp-HOH:
WATER

ChemComp-TYU:
TETRAHYDROURIDINE

ChemComp-CTN:
4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE

ChemComp-URI:
URIDINE

ChemComp-NH3:
AMMONIA

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / mouse / cytidine deaminase / zinc / 3-deazauridine / substrate dissociation / TETRAHYDROURIDINE / PROTEIN-INHIBITOR COMPLEX / ALTERNATE CONFORMATION OF ARG68 / CYTIDINE / URIDINE / PROTEIN-SUBSTRATE COMPLEX / SUBSTRATE-PRODUCT INTERMEDIATE

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