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Structure paper

TitleRegulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
Journal, issue, pagesJ. Mol. Biol., Vol. 349, Page 61-72, Year 2005
Publish dateDec 3, 2002 (structure data deposition date)
AuthorsGoulding, C.W. / Apostol, M.I. / Sawaya, M.R. / Phillips, M. / Parseghian, A. / Eisenberg, D.
External linksJ. Mol. Biol. / PubMed:15876368
MethodsX-ray diffraction
Resolution1.6 - 2.5 Å
Structure data

PDB-1nbu:
7,8-Dihydroneopterin Aldolase Complexed with Product From Mycobacterium Tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-1z9w:
Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-PH2:
2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
  • mycobacterium tuberculosis h37rv (bacteria)
KeywordsLYASE / anti-parallel / beta-sheet / two alpha helices / Structural Genomics / PSI / Protein Structure Initiative / TB Structural Genomics Consortium / TBSGC / FOLB / MYCOBACTERIUM TUBERCULOSIS / TB Structural Genomics / Mycobacterium Tuberculosis Structural Proteomics Project / XMTB

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