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Structure paper

TitleStructural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 116, Page 39-50, Year 2004
Publish dateDec 17, 2003 (structure data deposition date)
AuthorsChapados, B.R. / Hosfield, D.J. / Han, S. / Qiu, J. / Yelent, B. / Shen, B. / Tainer, J.A.
External linksCell(Cambridge,Mass. ) / PubMed:14718165
MethodsX-ray diffraction
Resolution1.8 - 2.8 Å
Structure data

PDB-1rwz:
Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) from A. fulgidus
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1rxm:
C-terminal region of FEN-1 bound to A. fulgidus PCNA
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1rxv:
Crystal Structure of A. Fulgidus FEN-1 bound to DNA
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1rxw:
Crystal structure of A. fulgidus FEN-1 bound to DNA
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1rxz:
C-terminal region of A. fulgidus FEN-1 complexed with A. fulgidus PCNA
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • archaeoglobus fulgidus (archaea)
KeywordsREPLICATION / sliding clamp / torus / processivity factor / beta-zipper / hydrophobic anchor / HYDROLASE/DNA / helical clamp / helix-3 turn-helix / 3' flap binding site / protein-dna complex / dna repair / dna replication / HYDROLASE-DNA COMPLEX / hydrophobic wedge / interdomain connecting loop

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