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TitleStructure of the Plasmodium falciparum triosephosphate isomerase-phosphoglycolate complex in two crystal forms: characterization of catalytic loop open and closed conformations in the ligand-bound state
Journal, issue, pagesBiochemistry, Vol. 41, Page 13178-13188, Year 2002
Publish dateJun 10, 2002 (structure data deposition date)
AuthorsParthasarathy, S. / Ravindra, G. / Balaram, H. / Balaram, P. / Murthy, M.R.
External linksBiochemistry / PubMed:12403619
MethodsX-ray diffraction
Resolution1.9 - 2.8 Å
Structure data

PDB-1lyx:
Plasmodium Falciparum Triosephosphate Isomerase (PfTIM)-Phosphoglycolate complex
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1lzo:
Plasmodium Falciparum Triosephosphate Isomerase-Phosphoglycolate Complex
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-PGA:
2-PHOSPHOGLYCOLIC ACID

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsISOMERASE / TIM barrels / beta-alpha barrels / Triosephosphate Isomerase; Phosphoglycolate; Loop Dynamics; Loop Open Conformation

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