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-Structure paper
Title | Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design. |
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Journal, issue, pages | J. Med. Chem., Vol. 43, Page 3377-3385, Year 2000 |
Publish date | Mar 7, 2001 (structure data deposition date) |
Authors | Gavuzzo, E. / Pochetti, G. / Mazza, F. / Gallina, C. / Gorini, B. / D'Alessio, S. / Pieper, M. / Tschesche, H. / Tucker, P.A. |
External links | J. Med. Chem. / PubMed:10978185 |
Methods | X-ray diffraction |
Resolution | 1.2 - 1.4 Å |
Structure data | PDB-1i73: PDB-1i76: |
Chemicals | ChemComp-CA: ChemComp-ZN: ChemComp-HOH: ChemComp-BSI: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / METALLOPROTEASE-INHIBITOR complex / HYDROLASE-HYDROLASE INHIBITOR complex / HYDROLASE / COMPLEX (METALLOPROTEASE-INHIBITOR) |