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Showing 1 - 50 of 58 items for (author: dhingra & y)

EMDB-75279: 
Closed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a closed active site (closed TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75280: 
Open1 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75281: 
Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75282: 
Open3 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

PDB-10ma: 
Closed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a closed active site (closed TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

PDB-10mb: 
Open1 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

PDB-10mc: 
Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

PDB-10md: 
Open3 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-27159: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/PAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-27160: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/Processed prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-27161: 
Type I-C Cas4-Cas1-Cas2 complex bound to half-site integration intermediate (HSI)
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-27162: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/NoPAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-27769: 
Type I-C Cas4-Cas1-Cas2 complex bound to a 24 bp duplex PAM/PAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

PDB-8d3l: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/PAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

PDB-8d3m: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/Processed prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

PDB-8d3p: 
Type I-C Cas4-Cas1-Cas2 complex bound to half-site integration intermediate (HSI)
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

PDB-8d3q: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/NoPAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-26281: 
TMEM106B(120-254) singlet amyloid fibril from dementia with Lewy bodies (DLB).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26282: 
TMEM106B(120-254) doublet amyloid fibril from dementia with Lewy bodies (DLB).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26283: 
Low-resolution map of tau filament from progressive supranuclear palsy (PSP) case 3.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26284: 
TMEM106B(120-254) singlet amyloid fibril from progressive supranuclear palsy (PSP) case 1.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26285: 
TMEM106B(120-254) singlet amyloid fibril from progressive supranuclear palsy (PSP) case 2.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26286: 
TMEM106B(120-254) doublet amyloid fibril from progressive supranuclear palsy (PSP) case 2.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26268: 
High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1
Method: helical / : FItzpatrick AWP, Stowell MHB

EMDB-26273: 
TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2
Method: helical / : Fitzpatrick AWP, Stowell MHB

EMDB-26274: 
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1)
Method: helical / : Fitzpatrick AWP, Stowell MHB

EMDB-26275: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2)
Method: helical / : Fitzpatrick AWP, Stowell MHB

EMDB-26276: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4).
Method: helical / : Fitzpatrick AWP, Stowell MHB

EMDB-26277: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

EMDB-26278: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

EMDB-26279: 
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Fitzpatrick AWP, Stowell MHB

PDB-7u0z: 
High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1
Method: helical / : FItzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u10: 
TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u11: 
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u12: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u13: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u14: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u15: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u16: 
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u17: 
TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u18: 
TMEM106B(120-254) T185S protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

EMDB-26287: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26288: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B (case 6).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26289: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 5).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26290: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26291: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 3).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26292: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 3).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26293: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26294: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26295: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
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