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Showing all 50 items for (author: dhingra & y)

EMDB-27159: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/PAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-27160: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/Processed prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-27161: 
Type I-C Cas4-Cas1-Cas2 complex bound to half-site integration intermediate (HSI)
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-27162: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/NoPAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-27769: 
Type I-C Cas4-Cas1-Cas2 complex bound to a 24 bp duplex PAM/PAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

PDB-8d3l: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/PAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

PDB-8d3m: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/Processed prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

PDB-8d3p: 
Type I-C Cas4-Cas1-Cas2 complex bound to half-site integration intermediate (HSI)
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

PDB-8d3q: 
Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/NoPAM prespacer
Method: single particle / : Dhingra Y, Suresh SK, Juneja P, Sashital DG

EMDB-26281: 
TMEM106B(120-254) singlet amyloid fibril from dementia with Lewy bodies (DLB).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26282: 
TMEM106B(120-254) doublet amyloid fibril from dementia with Lewy bodies (DLB).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26283: 
Low-resolution map of tau filament from progressive supranuclear palsy (PSP) case 3.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26284: 
TMEM106B(120-254) singlet amyloid fibril from progressive supranuclear palsy (PSP) case 1.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26285: 
TMEM106B(120-254) singlet amyloid fibril from progressive supranuclear palsy (PSP) case 2.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26286: 
TMEM106B(120-254) doublet amyloid fibril from progressive supranuclear palsy (PSP) case 2.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26268: 
High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1
Method: helical / : FItzpatrick AWP, Stowell MHB

EMDB-26273: 
TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2
Method: helical / : Fitzpatrick AWP, Stowell MHB

EMDB-26274: 
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1)
Method: helical / : Fitzpatrick AWP, Stowell MHB

EMDB-26275: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2)
Method: helical / : Fitzpatrick AWP, Stowell MHB

EMDB-26276: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4).
Method: helical / : Fitzpatrick AWP, Stowell MHB

EMDB-26277: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

EMDB-26278: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

EMDB-26279: 
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Fitzpatrick AWP, Stowell MHB

PDB-7u0z: 
High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1
Method: helical / : FItzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u10: 
TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u11: 
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u12: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u13: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u14: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u15: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u16: 
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u17: 
TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

PDB-7u18: 
TMEM106B(120-254) T185S protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA

EMDB-26287: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26288: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B (case 6).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26289: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 5).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26290: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26291: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 3).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26292: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 3).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26293: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26294: 
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26295: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-26296: 
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP

EMDB-20806: 
Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform
Method: single particle / : Kim J, Tan YZ

PDB-6ukj: 
Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform
Method: single particle / : Kim J, Tan YZ, Wicht KJ, Erramilli SK, Dhingra SK, Okombo J, Vendome J, Hagenah LM, Giacometti SI, Warren AL, Nosol K, Roepe PD, Potter CS, Carragher B, Kossiakoff AA, Quick M, Fidock DA, Mancia F

EMDB-20127: 
Bacillus halodurans Cas1-Cas2 complex in presence of target CRISPR DNA
Method: single particle / : Sashital DG, Lee H, Dhingra Y

EMDB-20128: 
Bacillus halodurans Cas4-Cas1-Cas2 asymmetrical complex in presence of target CRISPR DNA
Method: single particle / : Sashital DG, Lee H, Dhingra Y

EMDB-20129: 
Bacillus halodurans Cas4-Cas1-Cas2 symmetrical complex in presence of target CRISPR DNA
Method: single particle / : Sashital DG, Lee H, Dhingra Y

EMDB-20130: 
Bacillus halodurans Cas4-Cas1-Cas2 asymmetrical complex in presence of prespacer DNA
Method: single particle / : Sashital DG, Lee H, Dhingra Y

EMDB-20131: 
Bacillus halodurans Cas4-Cas1-Cas2 symmetrical complex in presence of prespacer DNA
Method: single particle / : Sashital DG, Lee H, Dhingra Y
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