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8S7L
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BU of 8s7l by Molmil
Crystal structure of a double mutant of VirB8-like OrfG central and C-terminal domains of Streptococcus thermophilus ICESt3 (Gram positive conjugative type IV secretion system).
Descriptor: Putative transfer protein
Authors:Favier, F, Didierjean, C, Maffo-Woulefack, R, Douzi, B, Leblond-Bourget, N.
Deposit date:2024-03-03
Release date:2025-03-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Elucidating assembly and function of VirB8 cell wall subunits refines the DNA translocation model in Gram-positive T4SSs.
Sci Adv, 11, 2025
3GMC
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BU of 3gmc by Molmil
Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase with substrate bound
Descriptor: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxy-6-methylpyridine-3-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE
Authors:McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E.
Deposit date:2009-03-13
Release date:2009-04-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications.
Biochemistry, 48, 2009
3GMB
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BU of 3gmb by Molmil
Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase
Descriptor: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E.
Deposit date:2009-03-13
Release date:2009-04-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications.
Biochemistry, 48, 2009
7PKW
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BU of 7pkw by Molmil
Crystal structure of VIRB8-like OrfG central and C-terminal domains of Streptococcus thermophilus ICESt3 (Gram positive conjugative type IV secretion system).
Descriptor: GLYCEROL, Putative transfer protein, SULFATE ION
Authors:Favier, F, Didierjean, C, Cappele, J, Douzi, B, Leblond-Bourget, N.
Deposit date:2021-08-27
Release date:2022-09-07
Last modified:2025-03-12
Method:X-RAY DIFFRACTION (1.835 Å)
Cite:Elucidating assembly and function of VirB8 cell wall subunits refines the DNA translocation model in Gram-positive T4SSs.
Sci Adv, 11, 2025
4BAY
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BU of 4bay by Molmil
Phosphomimetic mutant of LSD1-8a splicing variant in complex with CoREST
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1
Authors:Toffolo, E, Paganini, L, Rusconi, F, Tortorici, M, Pilotto, S, Verpelli, C, Tedeschi, G, Maffioli, E, Sala, C, Mattevi, A, Battaglioli, E.
Deposit date:2012-09-17
Release date:2013-11-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Phosphorylation of Neuronal Lysine-Specific Demethylase 1Lsd1/Kdm1A Impairs Transcriptional Repression by Regulating Interaction with Corest and Histone Deacetylases Hdac1/2.
J.Neurochem., 128, 2014
7QPG
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BU of 7qpg by Molmil
Human RZZ kinetochore corona complex.
Descriptor: Centromere/kinetochore protein zw10 homolog, Kinetochore-associated protein 1, Protein zwilch homolog
Authors:Raisch, T, Ciossani, G, d'Amico, E, Cmetowski, V, Carmignani, S, Maffini, S, Merino, F, Wohlgemuth, S, Vetter, I.R, Raunser, S, Musacchio, A.
Deposit date:2022-01-04
Release date:2022-03-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores.
Embo J., 41, 2022
2Z7B
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BU of 2z7b by Molmil
Crystal Structure of Mesorhizobium loti 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase
Descriptor: MANGANESE (II) ION, Mlr6791 protein
Authors:McCulloch, K.M, Mukherjee, T, Ealick, S.E, Begley, T.P.
Deposit date:2007-08-17
Release date:2007-11-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Gene Identification and Structural Characterization of the Pyridoxal 5'-Phosphate Degradative Protein 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate Decarboxylase from Mesorhizobium loti MAFF303099
Biochemistry, 46, 2007
2MH5
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BU of 2mh5 by Molmil
Structure and NMR assignments of lantibiotic NAI-107 in DPC micelles
Descriptor: Lantibiotic 107891, dodecyl 2-(trimethylammonio)ethyl phosphate
Authors:Munch, D, Muller, A, Schneider, T, Kohl, B, Wenzel, M, Bandow, J, Maffioli, S, Sosio, M, Donadio, S, Wimmer, R, Sahl, H.
Deposit date:2013-11-18
Release date:2014-03-05
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions.
J.Biol.Chem., 289, 2014
1T1V
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BU of 1t1v by Molmil
Crystal Structure of the Glutaredoxin-like Protein SH3BGRL3 at 1.6 A resolution
Descriptor: ACETIC ACID, GLYCEROL, SH3 domain-binding glutamic acid-rich protein-like 3, ...
Authors:Nardini, M, Mazzocco, M, Massaro, M, Maffei, M, Vergano, A, Donadini, A, Scartezzini, M, Bolognesi, M.
Deposit date:2004-04-19
Release date:2004-06-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the glutaredoxin-like protein SH3BGRL3 at 1.6 A resolution
Biochem.Biophys.Res.Commun., 318, 2004
5X21
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BU of 5x21 by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM)
Descriptor: (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zhang, Y, Ebright, R.
Deposit date:2017-01-29
Release date:2017-07-05
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.323 Å)
Cite:Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Cell, 169, 2017
5X22
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BU of 5x22 by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zhang, Y, Ebright, R.
Deposit date:2017-01-29
Release date:2017-07-05
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Cell, 169, 2017
8EVM
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BU of 8evm by Molmil
De novo design of chlorophyll special pair containing protein assemblies
Descriptor: Chlorophyll dimer protein designs, Special Pair 3 (SP3x)
Authors:Bera, A.K, Ennist, N.M.
Deposit date:2022-10-20
Release date:2024-05-15
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:De novo design of proteins housing excitonically coupled chlorophyll special pairs.
Nat.Chem.Biol., 20, 2024
7UNH
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BU of 7unh by Molmil
De novo designed chlorophyll dimer protein in apo state, SP2
Descriptor: 1,2-ETHANEDIOL, SP2 designed chlorophyll dimer protein
Authors:Kennedy, M.A, Stoddard, B.L, Ennist, N.M.
Deposit date:2022-04-11
Release date:2023-04-19
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:De novo design of proteins housing excitonically coupled chlorophyll special pairs.
Nat.Chem.Biol., 2024
7UNI
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BU of 7uni by Molmil
De novo designed chlorophyll dimer protein with Zn pheophorbide a methyl ester, SP2-ZnPPaM
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, SP2-ZnPPaM designed chlorophyll dimer protein, ...
Authors:Kennedy, M.A, Stoddard, B.L, Ennist, N.M.
Deposit date:2022-04-11
Release date:2023-04-19
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:De novo design of proteins housing excitonically coupled chlorophyll special pairs.
Nat.Chem.Biol., 2024
7UNJ
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BU of 7unj by Molmil
De novo designed chlorophyll dimer protein with Zn pheophorbide a methyl ester matching geometry of purple bacterial special pair, SP1-ZnPPaM
Descriptor: 1,2-ETHANEDIOL, SP1-ZnPPaM designed chlorophyll dimer protein, SULFATE ION, ...
Authors:Kennedy, M.A, Stoddard, B.L, Ennist, N.M.
Deposit date:2022-04-11
Release date:2023-04-19
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:De novo design of proteins housing excitonically coupled chlorophyll special pairs.
Nat.Chem.Biol., 2024
8ARF
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BU of 8arf by Molmil
Crystal structure of the N-terminal parallel dimeric coiled-coil region of the human kinetochore associated protein Spindly
Descriptor: Protein Spindly
Authors:Perrakis, A, Ahmad, M.U.
Deposit date:2022-08-16
Release date:2022-09-07
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin.
J.Cell Biol., 221, 2022
6EQT
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BU of 6eqt by Molmil
CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE PROTEIN CENP-N
Descriptor: Centromere protein N
Authors:Pentakota, S, Vetter, I.R, Petrovic, A, Musacchio, A.
Deposit date:2017-10-15
Release date:2018-01-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.735 Å)
Cite:Decoding the centromeric nucleosome through CENP-N.
Elife, 6, 2017
6C0W
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BU of 6c0w by Molmil
Cryo-EM structure of human kinetochore protein CENP-N with the centromeric nucleosome containing CENP-A
Descriptor: 147 mer DNA, Centromere protein N, Histone H2A, ...
Authors:Zhou, K, Pentakota, S, Vetter, I.R, Morgan, G.P, Petrovic, A, Musacchio, A, Luger, K.
Deposit date:2018-01-02
Release date:2018-01-17
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Decoding the centromeric nucleosome through CENP-N.
Elife, 6, 2017
7OK3
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BU of 7ok3 by Molmil
Crystal Structure of KRasG13C in Complex with Nucleotide-based Covalent Inhibitor edaGDP
Descriptor: Isoform 2B of GTPase KRas, edaGDP
Authors:Goebel, L, Mueller, M.P, Rauh, D.
Deposit date:2021-05-17
Release date:2022-08-03
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors.
Elife, 12, 2023
7OK4
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BU of 7ok4 by Molmil
Crystal Structure of KRasG13C in Complex with Nucleotide-based covalent Inhibitor bdaGDP
Descriptor: Isoform 2B of GTPase KRas, bdaGDP
Authors:Goebel, L, Mueller, M.P, Rauh, D.
Deposit date:2021-05-17
Release date:2022-08-03
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors.
Elife, 12, 2023
2Z9W
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BU of 2z9w by Molmil
Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxal
Descriptor: 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, Aspartate aminotransferase, GLYCEROL, ...
Authors:Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T.
Deposit date:2007-09-26
Release date:2007-11-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099
J.Biol.Chem., 283, 2008
2Z9U
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BU of 2z9u by Molmil
Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti at 2.0 A resolution
Descriptor: Aspartate aminotransferase, GLYCEROL, SULFATE ION
Authors:Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T.
Deposit date:2007-09-26
Release date:2007-11-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099
J.Biol.Chem., 283, 2008
2Z9V
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BU of 2z9v by Molmil
Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxamine
Descriptor: 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Aspartate aminotransferase, GLYCEROL, ...
Authors:Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T.
Deposit date:2007-09-26
Release date:2007-11-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099
J.Biol.Chem., 283, 2008
2Z9X
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BU of 2z9x by Molmil
Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxyl-L-alanine
Descriptor: 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, ALANINE, Aspartate aminotransferase, ...
Authors:Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T.
Deposit date:2007-09-26
Release date:2007-11-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099
J.Biol.Chem., 283, 2008
5UAO
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BU of 5uao by Molmil
Crystal structure of MibH, a lathipeptide tryptophan 5-halogenase
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Tryptophane-5-halogenase
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2016-12-19
Release date:2017-01-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.
ACS Chem. Biol., 12, 2017

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