Entry | Database: PDB / ID: 5g1e |
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Title | The complex structure of syntenin-1 PDZ domain with c-terminal extension |
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Components | SYNTENIN-1 |
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Keywords | SIGNALING PROTEIN |
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Function / homology | Function and homology information
Neurofascin interactions / RIPK1-mediated regulated necrosis / Regulation of necroptotic cell death / Ephrin signaling / interleukin-5 receptor complex / interleukin-5 receptor binding / positive regulation of extracellular exosome assembly / syndecan binding / neurexin family protein binding / presynapse assembly ...Neurofascin interactions / RIPK1-mediated regulated necrosis / Regulation of necroptotic cell death / Ephrin signaling / interleukin-5 receptor complex / interleukin-5 receptor binding / positive regulation of extracellular exosome assembly / syndecan binding / neurexin family protein binding / presynapse assembly / positive regulation of exosomal secretion / frizzled binding / negative regulation of receptor internalization / Neutrophil degranulation / positive regulation of transforming growth factor beta receptor signaling pathway / growth factor binding / regulation of mitotic cell cycle / positive regulation of phosphorylation / positive regulation of epithelial to mesenchymal transition / cell adhesion molecule binding / protein sequestering activity / phosphatidylinositol-4,5-bisphosphate binding / ionotropic glutamate receptor binding / ephrin receptor binding / adherens junction / melanosome / presynapse / positive regulation of cell growth / nuclear membrane / Ras protein signal transduction / cytoskeleton / positive regulation of cell migration / membrane raft / protein heterodimerization activity / focal adhesion / positive regulation of cell population proliferation / endoplasmic reticulum membrane / protein-containing complex binding / negative regulation of transcription by RNA polymerase II / extracellular exosome / nucleoplasm / identical protein binding / plasma membrane / cytoplasm / cytosolSimilarity search - Function : / PDZ domain / Pdz3 Domain / PDZ domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Roll / Mainly BetaSimilarity search - Domain/homology |
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Biological species | RATTUS NORVEGICUS (Norway rat) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.92 Å |
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Authors | Lee, I. / Kim, H. / Yun, J.H. / Lee, W. |
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Citation | Journal: Sci.Rep. / Year: 2016 Title: New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling. Authors: Choi, Y. / Yun, J.H. / Yoo, J. / Kim, H. / Lee, I. / Son, H.N. / Kim, I.S. / Yoon, H.S. / Zimmermann, P. / Couchman, J.R. / Cho, H.S. / Oh, E.S. / Lee, W. |
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History | Deposition | Mar 25, 2016 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Nov 23, 2016 | Provider: repository / Type: Initial release |
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Revision 1.1 | Mar 29, 2017 | Group: Other |
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Revision 1.2 | Jul 12, 2017 | Group: Refinement description / Category: software / Item: _software.name |
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Revision 1.3 | May 8, 2024 | Group: Data collection / Database references / Other Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf |
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