+Open data
-Basic information
Entry | Database: PDB / ID: 1ocp | ||||||
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Title | SOLUTION STRUCTURE OF OCT3 POU-HOMEODOMAIN | ||||||
Components | OCT-3 | ||||||
Keywords | DNA BINDING PROTEIN / DNA-BINDING PROTEIN | ||||||
Function / homology | Function and homology information ectodermal cell fate commitment / response to benzoic acid / mesodermal cell fate commitment / HMG box domain binding / trophectodermal cell fate commitment / blastocyst growth / regulation of asymmetric cell division / endodermal cell fate specification / endodermal cell fate commitment / germ-line stem cell population maintenance ...ectodermal cell fate commitment / response to benzoic acid / mesodermal cell fate commitment / HMG box domain binding / trophectodermal cell fate commitment / blastocyst growth / regulation of asymmetric cell division / endodermal cell fate specification / endodermal cell fate commitment / germ-line stem cell population maintenance / POU domain binding / negative regulation of calcium ion-dependent exocytosis / trophectodermal cell differentiation / female germ cell nucleus / germ cell nucleus / RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding / stem cell population maintenance / cell fate commitment / cytokine binding / somatic stem cell population maintenance / negative regulation of cell differentiation / : / blastocyst development / positive regulation of transcription initiation by RNA polymerase II / cis-regulatory region sequence-specific DNA binding / male germ cell nucleus / response to retinoic acid / lysine-acetylated histone binding / transcription repressor complex / cellular response to leukemia inhibitory factor / stem cell differentiation / chromatin DNA binding / gene expression / DNA-binding transcription activator activity, RNA polymerase II-specific / DNA-binding transcription factor binding / transcription regulator complex / sequence-specific DNA binding / RNA polymerase II-specific DNA-binding transcription factor binding / transcription cis-regulatory region binding / transcription by RNA polymerase II / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / negative regulation of gene expression / negative regulation of DNA-templated transcription / chromatin binding / ubiquitin protein ligase binding / regulation of transcription by RNA polymerase II / positive regulation of gene expression / positive regulation of DNA-templated transcription / chromatin / regulation of DNA-templated transcription / nucleolus / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / nucleoplasm / nucleus / cytoplasm Similarity search - Function | ||||||
Biological species | Mus musculus (house mouse) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Morita, E.H. / Hayashi, F. / Shirakawa, M. / Kyogoku, Y. | ||||||
Citation | Journal: Protein Sci. / Year: 1995 Title: Structure of the Oct-3 POU-Homeodomain in Solution, as Determined by Triple Resonance Heteronuclear Multidimensional NMR Spectroscopy Authors: Morita, E.H. / Shirakawa, M. / Hayashi, F. / Imagawa, M. / Kyogoku, Y. #1: Journal: FEBS Lett. / Year: 1993 Title: Secondary Structure of the Oct-3 POU Homeodomain as Determined by 1H-15N NMR Spectroscopy Authors: Morita, E.H. / Shirakawa, M. / Hayashi, F. / Imagawa, K. / Kyogoku, Y. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1ocp.cif.gz | 452.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1ocp.ent.gz | 378.2 KB | Display | PDB format |
PDBx/mmJSON format | 1ocp.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1ocp_validation.pdf.gz | 344.8 KB | Display | wwPDB validaton report |
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Full document | 1ocp_full_validation.pdf.gz | 490.3 KB | Display | |
Data in XML | 1ocp_validation.xml.gz | 27.9 KB | Display | |
Data in CIF | 1ocp_validation.cif.gz | 44.5 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/oc/1ocp ftp://data.pdbj.org/pub/pdb/validation_reports/oc/1ocp | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 8029.471 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Mus musculus (house mouse) / Gene: T7 GENE 1 UNDER CONTROL OF THE / Plasmid: PAR2113 / Species (production host): Escherichia coli Gene (production host): T7 GENE 1 UNDER CONTROL OF THE LAC UV5 PROMOTER Production host: Escherichia coli BL21(DE3) (bacteria) / Strain (production host): BL21(DE3) / References: UniProt: P20263 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Crystal grow | *PLUS Method: other / Details: NMR |
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-Processing
Software |
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NMR software | Name: X-PLOR / Version: 3.1 / Developer: BRUNGER / Classification: refinement | ||||||||||||
NMR ensemble | Conformers submitted total number: 20 |