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Yorodumi- PDB-1cdq: STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1cdq | ||||||
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Title | STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59 | ||||||
Components | CD59 | ||||||
Keywords | COMPLEMENT REGULATORY PROTEIN | ||||||
Function / homology | Function and homology information negative regulation of activation of membrane attack complex / complement binding / regulation of complement-dependent cytotoxicity / regulation of complement activation / Cargo concentration in the ER / COPII-mediated vesicle transport / tertiary granule membrane / COPI-mediated anterograde transport / specific granule membrane / transport vesicle ...negative regulation of activation of membrane attack complex / complement binding / regulation of complement-dependent cytotoxicity / regulation of complement activation / Cargo concentration in the ER / COPII-mediated vesicle transport / tertiary granule membrane / COPI-mediated anterograde transport / specific granule membrane / transport vesicle / endoplasmic reticulum-Golgi intermediate compartment membrane / Regulation of Complement cascade / ER to Golgi transport vesicle membrane / blood coagulation / vesicle / cell surface receptor signaling pathway / Golgi membrane / external side of plasma membrane / focal adhesion / endoplasmic reticulum membrane / Neutrophil degranulation / cell surface / extracellular space / extracellular exosome / membrane / plasma membrane Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Fletcher, C.M. / Harrison, R.A. / Lachmann, P.J. / Neuhaus, D. | ||||||
Citation | Journal: Structure / Year: 1994 Title: Structure of a soluble, glycosylated form of the human complement regulatory protein CD59. Authors: Fletcher, C.M. / Harrison, R.A. / Lachmann, P.J. / Neuhaus, D. #1: Journal: Protein Sci. / Year: 1993 Title: Sequence-Specific 1H-NMR Assignments and Folding Topology of Human Cd59 Authors: Fletcher, C.M. / Harrison, R.A. / Lachmann, P.J. / Neuhaus, D. #2: Journal: Immunol.Res. / Year: 1993 Title: Membrane Defence Against Complement Lysis: The Structure and Biological Properties of Cd59 Authors: Davies, A. / Lachmann, P.J. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1cdq.cif.gz | 461.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1cdq.ent.gz | 400.7 KB | Display | PDB format |
PDBx/mmJSON format | 1cdq.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1cdq_validation.pdf.gz | 341.9 KB | Display | wwPDB validaton report |
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Full document | 1cdq_full_validation.pdf.gz | 506 KB | Display | |
Data in XML | 1cdq_validation.xml.gz | 33.5 KB | Display | |
Data in CIF | 1cdq_validation.cif.gz | 51.4 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/cd/1cdq ftp://data.pdbj.org/pub/pdb/validation_reports/cd/1cdq | HTTPS FTP |
-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 8970.106 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / References: UniProt: P13987 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Crystal grow | *PLUS Method: other / Details: NMR |
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-Processing
Software |
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NMR software | Name: X-PLOR / Developer: BRUNGER / Classification: refinement | ||||||||
NMR ensemble | Conformers submitted total number: 20 |