+Open data
-Basic information
Entry | Database: PDB chemical components / ID: ZD6 | ||||
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Name | Name: Wikipedia | Wikipedia - Vandetanib: Vandetanib, sold under the brand name Caprelsa, is an anti-cancer medication that is used for the treatment of certain tumours of the thyroid gland. It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase... | Comment | medication, anticancer, inhibitor*YM | |
-Chemical information
Composition | Formula: C22H24BrFN4O2 / Number of atoms: 54 / Formula weight: 475.354 / Formal charge: 0 | ||||||||||
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Others | Type: NON-POLYMER / PDB classification: HETAIN / Three letter code: ZD6 / Ideal coordinates details: Corina / Model coordinates PDB-ID: 2IVU | ||||||||||
History |
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External links | UniChem / BindingDB / Brenda / ChEBI / ChEMBL / ChemicalBook / CompTox / DailyMed / DrugBank / GtoPharmacology / Nikkaji / PubChem / PubChem_TPharma / SureChEMBL / ZINC / ChemSpider / Wikipedia search / Google search |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Details
-SMILES
CACTVS 3.385 | OpenEye OEToolkits 2.0.6 | |
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-SMILES CANONICAL
CACTVS 3.385 | OpenEye OEToolkits 2.0.6 | |
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-InChI
InChI 1.03 |
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-InChIKey
InChI 1.03 |
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-PDB entries
Showing all 1 items
PDB-2ivu:
Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor ZD6474