- PDB-4usv: Crystal structure of human soluble Adenylyl Cyclase with pyrophos... -
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基本情報
登録情報
データベース: PDB / ID: 4usv
タイトル
Crystal structure of human soluble Adenylyl Cyclase with pyrophosphate resulting from soaking with ATP and Calcium
要素
ADENYLATE CYCLASE TYPE 10
キーワード
LYASE (リアーゼ) / REACTION PRODUCT
機能・相同性
機能・相同性情報
negative regulation of cardiac muscle cell contraction / astrocyte end-foot / mitochondrial ATP transmembrane transport / epithelial cilium movement involved in extracellular fluid movement / bicarbonate binding / neuron projection retraction / positive regulation of glycogen catabolic process / central region of growth cone / cellular response to inorganic substance / regulation of mitophagy ...negative regulation of cardiac muscle cell contraction / astrocyte end-foot / mitochondrial ATP transmembrane transport / epithelial cilium movement involved in extracellular fluid movement / bicarbonate binding / neuron projection retraction / positive regulation of glycogen catabolic process / central region of growth cone / cellular response to inorganic substance / regulation of mitophagy / glucose catabolic process / regulation of membrane repolarization / アデニル酸シクラーゼ / basal part of cell / positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway / cAMP biosynthetic process / positive regulation of ossification / adenylate cyclase activity / positive regulation of protein targeting to mitochondrion / positive regulation of reactive oxygen species biosynthetic process / neuron projection extension / positive regulation of vascular associated smooth muscle cell apoptotic process / positive regulation of mitochondrial depolarization / positive regulation of ATP biosynthetic process / positive regulation of cardiac muscle hypertrophy / positive regulation of cardiac muscle cell apoptotic process / spermatid development / negative regulation of mitochondrial membrane potential / positive regulation of axon extension / Hedgehog 'off' state / negative regulation of reactive oxygen species biosynthetic process / neuron projection maintenance / positive regulation of peptidyl-threonine phosphorylation / 繊毛 / manganese ion binding / ATPase binding / 細胞骨格 / intracellular signal transduction / apical plasma membrane / neuronal cell body / 樹状突起 / perinuclear region of cytoplasm / magnesium ion binding / ミトコンドリア / extracellular region / ATP binding / 細胞核 / 細胞質基質 / 細胞質 類似検索 - 分子機能
解像度: 2→87.36 Å / Cor.coef. Fo:Fc: 0.971 / Cor.coef. Fo:Fc free: 0.947 / SU B: 7.852 / SU ML: 0.106 / 交差検証法: THROUGHOUT / ESU R: 0.141 / ESU R Free: 0.139 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES WITH TLS ADDED
Rfactor
反射数
%反射
Selection details
Rfree
0.20893
1929
5.1 %
RANDOM
Rwork
0.15994
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obs
0.16235
35990
99.95 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK