登録情報 | データベース: PDB / ID: 1xx0 |
---|
タイトル | Structure of the C-terminal PH domain of human pleckstrin |
---|
要素 | Pleckstrin |
---|
キーワード | LIPID BINDING PROTEIN / pleckstrin / PH / C-terminal (C末端) / pleckstrin homology |
---|
機能・相同性 | 機能・相同性情報
positive regulation of inositol-polyphosphate 5-phosphatase activity / protein secretion by platelet / phospholipase C-inhibiting G protein-coupled receptor signaling pathway / regulation of cell diameter / thrombin-activated receptor signaling pathway / negative regulation of inositol phosphate biosynthetic process / negative regulation of calcium-mediated signaling / positive regulation of actin filament depolymerization / protein kinase C signaling / platelet degranulation ...positive regulation of inositol-polyphosphate 5-phosphatase activity / protein secretion by platelet / phospholipase C-inhibiting G protein-coupled receptor signaling pathway / regulation of cell diameter / thrombin-activated receptor signaling pathway / negative regulation of inositol phosphate biosynthetic process / negative regulation of calcium-mediated signaling / positive regulation of actin filament depolymerization / protein kinase C signaling / platelet degranulation / negative regulation of G protein-coupled receptor signaling pathway / phosphatidylinositol metabolic process / positive regulation of actin filament bundle assembly / positive regulation of integrin activation / vesicle docking involved in exocytosis / cell projection organization / ruffle organization / positive regulation of platelet activation / phosphatidylinositol-3,4-bisphosphate binding / cortical actin cytoskeleton organization / hematopoietic progenitor cell differentiation / protein kinase C binding / integrin-mediated signaling pathway / 血小板 / ruffle membrane / Platelet degranulation / actin cytoskeleton organization / protein homodimerization activity / extracellular region / 生体膜 / 細胞膜 / 細胞質基質 / 細胞質類似検索 - 分子機能 Pleckstrin, DEP domain / : / Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) / DEP domain profile. / Domain found in Dishevelled, Egl-10, and Pleckstrin / DEP domain / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / PH domain / PH domain profile. ...Pleckstrin, DEP domain / : / Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) / DEP domain profile. / Domain found in Dishevelled, Egl-10, and Pleckstrin / DEP domain / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / PH domain / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / PH-like domain superfamily / Winged helix DNA-binding domain superfamily / Roll / Winged helix-like DNA-binding domain superfamily / Mainly Beta類似検索 - ドメイン・相同性 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | 溶液NMR |
---|
データ登録者 | Edlich, C. / Stier, G. / Simon, B. / Sattler, M. / Muhle-Goll, C. |
---|
引用 | ジャーナル: STRUCTURE / 年: 2005 タイトル: Structure and phosphatidylinositol-(3,4)-bisphosphate binding of the C-terminal PH domain of human pleckstrin 著者: Edlich, C. / Stier, G. / Simon, B. / Sattler, M. / Muhle-Goll, C. |
---|
履歴 | 登録 | 2004年11月3日 | 登録サイト: RCSB / 処理サイト: PDBJ |
---|
改定 1.0 | 2005年5月3日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2008年4月30日 | Group: Version format compliance |
---|
改定 1.2 | 2011年7月13日 | Group: Version format compliance |
---|
改定 1.3 | 2022年3月2日 | Group: Database references / Derived calculations カテゴリ: database_2 / pdbx_struct_assembly ...database_2 / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
---|
|
---|