登録情報 データベース : PDB / ID : 1pn5 構造の表示 ダウンロードとリンクタイトル NMR structure of the NALP1 Pyrin domain (PYD) 要素NACHT-, LRR- and PYD-containing protein 2 詳細 キーワード APOPTOSIS (アポトーシス) / 5 ALPHA-HELIX BUNDLE機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
NLRP1 inflammasome complex assembly / cysteine-type endopeptidase activator activity / NLRP1 inflammasome complex / canonical inflammasome complex / The NLRP1 inflammasome / self proteolysis / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素 / IgG binding / pattern recognition receptor activity / pattern recognition receptor signaling pathway ... NLRP1 inflammasome complex assembly / cysteine-type endopeptidase activator activity / NLRP1 inflammasome complex / canonical inflammasome complex / The NLRP1 inflammasome / self proteolysis / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素 / IgG binding / pattern recognition receptor activity / pattern recognition receptor signaling pathway / cellular response to UV-B / stress-activated protein kinase signaling cascade / pyroptosis / antiviral innate immune response / cysteine-type endopeptidase activator activity involved in apoptotic process / response to muramyl dipeptide / signaling adaptor activity / molecular condensate scaffold activity / positive regulation of interleukin-1 beta production / 加水分解酵素; 酸無水物に作用; 酸無水物に作用・細胞または細胞小器官の運動に関与 / protein homooligomerization / positive regulation of inflammatory response / activation of cysteine-type endopeptidase activity involved in apoptotic process / : / double-stranded RNA binding / peptidase activity / regulation of inflammatory response / double-stranded DNA binding / defense response to virus / neuron apoptotic process / regulation of apoptotic process / defense response to bacterium / protein domain specific binding / apoptotic process / 核小体 / enzyme binding / ATP hydrolysis activity / extracellular region / 核質 / ATP binding / 細胞核 / 細胞質基質 / 細胞質 類似検索 - 分子機能 FIIND domain / Function to find / FIIND domain profile. / CARD8/ASC/NALP1, CARD domain / NACHT, LRR and PYD domains-containing protein, helical domain HD2 / NLRC4 helical domain HD2 / NOD2, winged helix domain / NOD2 winged helix domain / Leucine rich repeat, ribonuclease inhibitor type / DAPIN domain ... FIIND domain / Function to find / FIIND domain profile. / CARD8/ASC/NALP1, CARD domain / NACHT, LRR and PYD domains-containing protein, helical domain HD2 / NLRC4 helical domain HD2 / NOD2, winged helix domain / NOD2 winged helix domain / Leucine rich repeat, ribonuclease inhibitor type / DAPIN domain / DAPIN domain profile. / PAAD/DAPIN/Pyrin domain / NACHT nucleoside triphosphatase / NACHT domain / NACHT-NTPase domain profile. / Death Domain, Fas / PAAD/DAPIN/Pyrin domain / Death Domain, Fas / IgG-binding B / B domain / M protein-type anchor domain / GA-like domain / GA-like domain / ロイシンリッチリピート / Immunoglobulin/albumin-binding domain superfamily / ロイシンリッチリピート / CARD domain / CARD caspase recruitment domain profile. / Caspase recruitment domain / YSIRK Gram-positive signal peptide / LPXTG cell wall anchor motif / Gram-positive cocci surface proteins LPxTG motif profile. / LPXTG cell wall anchor domain / Leucine-rich repeat profile. / Death-like domain superfamily / ロイシンリッチリピート / Leucine-rich repeat domain superfamily / P-loop containing nucleoside triphosphate hydrolase / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 Immunoglobulin G-binding protein G / NACHT, LRR and PYD domains-containing protein 1 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 溶液NMR / torsion angle dynamics 詳細データ登録者 Hiller, S. / Kohl, A. / Fiorito, F. / Herrmann, T. / Wider, G. / Tschopp, J. / Grutter, M.G. / Wuthrich, K. 引用ジャーナル : Structure / 年 : 2003タイトル : NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain著者 : Hiller, S. / Kohl, A. / Fiorito, F. / Herrmann, T. / Wider, G. / Tschopp, J. / Grutter, M.G. / Wuthrich, K. 履歴 登録 2003年6月12日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2003年10月7日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月29日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2021年10月27日 Group : Data collection / Database references / Derived calculationsカテゴリ : database_2 / pdbx_nmr_software ... database_2 / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _struct_ref_seq_dif.details
すべて表示 表示を減らす Remark 999 SEQUENCE Residues 1-58 are missing from the coordinates because they were not included in the model. ... SEQUENCE Residues 1-58 are missing from the coordinates because they were not included in the model. Residues 57 and 58 are independent linking residues, which have been inserted to provide distance and flexibiltiy in this two-domain fusion protein. Remark 650 HELIX Determination method: author