+データを開く
-基本情報
登録情報 | データベース: SASBDB / ID: SASDFW4 |
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試料 | Conformation of R8-15 human dystrophin fragment
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機能・相同性 | 機能・相同性情報 regulation of muscle system process / regulation of cellular response to growth factor stimulus / regulation of skeletal muscle contraction / syntrophin complex / synaptic signaling / regulation of voltage-gated calcium channel activity / negative regulation of peptidyl-cysteine S-nitrosylation / cardiac muscle cell action potential / positive regulation of sodium ion transmembrane transporter activity / dystrophin-associated glycoprotein complex ...regulation of muscle system process / regulation of cellular response to growth factor stimulus / regulation of skeletal muscle contraction / syntrophin complex / synaptic signaling / regulation of voltage-gated calcium channel activity / negative regulation of peptidyl-cysteine S-nitrosylation / cardiac muscle cell action potential / positive regulation of sodium ion transmembrane transporter activity / dystrophin-associated glycoprotein complex / cell-substrate junction / motile cilium assembly / peptide biosynthetic process / dystroglycan binding / regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion / vinculin binding / muscle cell development / costamere / neuron projection terminus / Striated Muscle Contraction / filopodium membrane / muscle organ development / structural constituent of muscle / myosin binding / muscle cell cellular homeostasis / maintenance of blood-brain barrier / nitric-oxide synthase binding / negative regulation of peptidyl-serine phosphorylation / Non-integrin membrane-ECM interactions / neuron development / regulation of ryanodine-sensitive calcium-release channel activity / regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion / regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum / cardiac muscle contraction / skeletal muscle tissue development / response to muscle stretch / positive regulation of neuron differentiation / regulation of heart rate / filopodium / sarcolemma / Z disc / structural constituent of cytoskeleton / positive regulation of neuron projection development / protein localization / actin binding / protein-containing complex assembly / postsynaptic membrane / cytoskeleton / membrane raft / synapse / cell surface / protein-containing complex / zinc ion binding / nucleus / plasma membrane / cytosol 類似検索 - 分子機能 |
登録者 |
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-構造の表示
構造ビューア | 分子: MolmilJmol/JSmol |
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-ダウンロードとリンク
-モデル
モデル #2888 | タイプ: atomic / カイ2乗値: 1.819 Omokage検索でこの集合体の類似形状データを探す (詳細) |
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-試料
試料 | 名称: Conformation of R8-15 human dystrophin fragment |
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バッファ | 名称: NaP 10 mM, NaCl 500 mM, EDTA 1 mM, Glycerol 2% / pH: 7.5 |
要素 #1554 | タイプ: protein / 記述: Human dystrophin central domain R8-15 fragment / 分子量: 100.208 / 分子数: 1 / 参照: UniProt: P11532 配列: MSYYHHHHHH DYDIPTTENL YFQGAMDPEF DCGSRKEALK GGLEKTVSLQ KDLSEMHEWM TQAEEEYLER DFEYKTPDEL QKAVEEMKRA KEEAQQKEAK VKLLTESVNS VIAQAPPVAQ EALKKELETL TTNYQWLCTR LNGKCKTLEE VWACWHELLS YLEKANKWLN ...配列: MSYYHHHHHH DYDIPTTENL YFQGAMDPEF DCGSRKEALK GGLEKTVSLQ KDLSEMHEWM TQAEEEYLER DFEYKTPDEL QKAVEEMKRA KEEAQQKEAK VKLLTESVNS VIAQAPPVAQ EALKKELETL TTNYQWLCTR LNGKCKTLEE VWACWHELLS YLEKANKWLN EVEFKLKTTE NIPGGAEEIS EVLDSLENLM RHSEDNPNQI RILAQTLTDG GVMDELINEE LETFNSRWRE LHEEAVRRQK LLEQSIQSAQ ETEKSLHLIQ ESLTFIDKQL AAYIADKVDA AQMPQEAQKI QSDLTSHEIS LEEMKKHNQG KEAAQRVLSQ IDVAQKKLQD VSMKFRLFQK PANFELRLQE SKMILDEVKM HLPALETKSV EQEVVQSQLN HCVNLYKSLS EVKSEVEMVI KTGRQIVQKK QTENPKELDE RVTALKLHYN ELGAKVTERK QQLEKCLKLS RKMRKEMNVL TEWLAATDME LTKRSAVEGM PSNLDSEVAW GKATQKEIEK QKVHLKSITE VGEALKTVLG KKETLVEDKL SLLNSNWIAV TSRAEEWLNL LLEYQKHMET FDQNVDHITK WIIQADTLLD ESEKKKPQQK EDVLKRLKAE LNDIRPKVDS TRDQAANLMA NRGDHCRKLV EPQISELNHR FAAISHRIKT GKASIPLKEL EQFNSDIQKL LEPLEAEIQQ GVNLKEEDFN KDMNEDNEGT VKELLQRGDN LQQRITDERK REEIKIKQQL LQTKHNALKD LRSQRRKKAL EISHQWYQYK RQADDLLKCL DDIEKKLASL PEPRDERKIK EIDRELQKKK EELNAVRRQA EGLSEDGAAM AVEPTQIQLS KRWREIESKF AQFRRLNFAQ |
-実験情報
ビーム | 設備名称: SOLEIL SWING / 地域: Saint-Aubin / 国: France / 線源: X-ray synchrotron / 波長: 0.1033 Å / スペクトロメータ・検出器間距離: 1.8 mm | ||||||||||||||||||
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検出器 | 名称: AVIEX PCCD170170 / タイプ: CCD | ||||||||||||||||||
スキャン | タイトル: Conformation of R8-15 human dystrophin fragment 測定日: 2015年9月23日 / セル温度: 15 °C / 照射時間: 1.5 sec. / フレーム数: 38 / 単位: 1/A /
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距離分布関数 P(R) | ソフトウェア P(R): GNOM 4.6 / ポイント数: 478 /
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結果 | Experimental MW: 88 kDa / カーブのタイプ: sec コメント: SEC-SAXS was performed at 15°C using the following parameters: Column: BioSEC5-500Å (4.6 mm id * 300 mm); Flow rate: 0.2 mL/min; Sample injection concentration: 4 mg/mL; Injection ...コメント: SEC-SAXS was performed at 15°C using the following parameters: Column: BioSEC5-500Å (4.6 mm id * 300 mm); Flow rate: 0.2 mL/min; Sample injection concentration: 4 mg/mL; Injection volume: 60μL. The data were collected through the SEC peak of the protein as a series of 38 x 1.5 second exposures. The experimental molecular weight was determined from the volume of correlation, Vc.
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