PDB-9qit: Crystal structure of a D-lactate dehydrogenase in complex with D-...

Basic information

• Entry: Database: PDB / ID: 9qit
• Title: Crystal structure of a D-lactate dehydrogenase in complex with D-lactate from Porcellio dilatatus
• Components: Glycolate oxidase
• Keywords: OXIDOREDUCTASE / Gut metagenome / Oxidoreductases / Lactate dehydrogenases
• Function / homology: FLAVIN-ADENINE DINUCLEOTIDE / : / LACTIC ACID
• Biological species: Porcellio dilatatus (crustacean)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.04 Å
• Authors: Borges, P.T. / Frazao, C. / Martins, L.O.

Funding support

Portugal, 1items

Organization	Grant number	Country
Foundation for Science and Technology (FCT)		Portugal

• Citation: Journal: Appl.Environ.Microbiol. / Year: 2025; Title: Shotgun metagenomic mining reveals a new FAD-dependent D-lactate dehydrogenase in an isopod gut microbiome.; Authors: Coelho, C. / Taborda, A. / Lorena, C. / Frazao, T. / Verissimo, A. / Borges, P.T. / Brissos, V. / Tiago, I. / Martins, L.O.

History

Deposition	Mar 17, 2025	Deposition site: PDBE / Processing site: PDBE
Revision 1.0	Dec 3, 2025	Provider: repository / Type: Initial release

Assembly

Deposited unit

A: Glycolate oxidase

B: Glycolate oxidase

C: Glycolate oxidase

D: Glycolate oxidase

E: Glycolate oxidase

F: Glycolate oxidase

G: Glycolate oxidase

H: Glycolate oxidase

hetero molecules

Summary:

• 399 kDa, 8 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	399,415	33
Polymers	391,762	8
Non-polymers	7,653	25
Water	0	0

1

A: Glycolate oxidase

E: Glycolate oxidase

hetero molecules

Summary:

• defined by author&software
• Evidence: gel filtration
• 100 kDa, 2 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	99,988	10
Polymers	97,941	2
Non-polymers	2,047	8
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Buried area	8970 Å2
ΔGint	-95 kcal/mol
Surface area	32360 Å2
Method	PISA

2

B: Glycolate oxidase

F: Glycolate oxidase

hetero molecules

Summary:

• defined by author&software
• 99.8 kDa, 2 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	99,840	8
Polymers	97,941	2
Non-polymers	1,899	6
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Buried area	8550 Å2
ΔGint	-77 kcal/mol
Surface area	32550 Å2
Method	PISA

3

C: Glycolate oxidase

G: Glycolate oxidase

hetero molecules

Summary:

• defined by author&software
• 99.8 kDa, 2 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	99,840	8
Polymers	97,941	2
Non-polymers	1,899	6
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Buried area	8610 Å2
ΔGint	-81 kcal/mol
Surface area	32090 Å2
Method	PISA

4

D: Glycolate oxidase

H: Glycolate oxidase

hetero molecules

Summary:

• defined by author&software
• 99.7 kDa, 2 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	99,748	7
Polymers	97,941	2
Non-polymers	1,807	5
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Buried area	8540 Å2
ΔGint	-79 kcal/mol
Surface area	31890 Å2
Method	PISA

Unit cell

Length a, b, c (Å)	127.225, 109.644, 143.437
Angle α, β, γ (deg.)	90.00, 98.26, 90.00
Int Tables number	4
Space group name H-M	P1211

Components

#1: Protein

A B C D E F G H
Glycolate oxidase

Details:

Mass: 48970.273 Da / Num. of mol.: 8
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Porcellio dilatatus (crustacean) / Gene: BDW27_113140 / Production host: Escherichia coli (E. coli)

#2: Chemical

A-501 E-502 F-501 G-501
ChemComp-GOL / GLYCEROL / GLYCERIN / PROPANE-1,2,3-TRIOL

Details:

Mass: 92.094 Da / Num. of mol.: 4 / Source method: obtained synthetically / Formula: C₃H₈O₃

#3: Chemical

A-502 B-501 C-501 D-501 E-501 F-502 G-502 H-501
ChemComp-LAC / LACTIC ACID

Details:

Mass: 90.078 Da / Num. of mol.: 8 / Source method: obtained synthetically / Formula: C₃H₆O₃

#4: Chemical

A-503 B-502 C-502 D-502 E-503 F-503 G-503 H-502
ChemComp-FAD / FLAVIN-ADENINE DINUCLEOTIDE

Details:

Mass: 785.550 Da / Num. of mol.: 8 / Source method: obtained synthetically / Formula: C₂₇H₃₃N₉O₁₅P₂ / Comment: FAD*YM

#5: Chemical

A-504 E-504 F-504 G-504 H-503
ChemComp-FE / FE (III) ION

Details:

Mass: 55.845 Da / Num. of mol.: 5 / Source method: obtained synthetically / Formula: Fe

• Has ligand of interest: N
• Has protein modification: N

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 2.61 ų/Da / Density % sol: 52.92 %
• Crystal grow: Temperature: 293 K / Method: vapor diffusion, hanging drop; Details: 0.2 M sodium formate, 0.1 M sodium phosphate pH 6.2, 20% (v/v) PEG Smear Medium and 10% (v/v) glycerol

Data collection

• Diffraction: Mean temperature: 100 K / Serial crystal experiment: N
• Diffraction source: Source: SYNCHROTRON / Site: ALBA / Beamline: XALOC / Wavelength: 0.97918 Å
• Detector: Type: DECTRIS PILATUS 6M / Detector: PIXEL / Date: Oct 19, 2023
• Radiation: Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 0.97918 Å / Relative weight: 1
• Reflection: Resolution: 3.04→88.11 Å / Num. obs: 48050 / % possible obs: 91.6 % / Redundancy: 3.2 % / CC_1/2: 0.985 / Net I/σ(I): 3.8
• Reflection shell: Resolution: 3.04→3.29 Å / Num. unique obs: 2402 / CC_1/2: 0.807

Processing

Software

Name	Version	Classification
PHENIX	(1.20.1_4487: ???)	refinement
XDS		data reduction
PHASER		phasing
XDS		data scaling

Refinement

Method to determine structure: MOLECULAR REPLACEMENT / Resolution: 3.04→88.11 Å / SU ML: 0.37 / Cross valid method: FREE R-VALUE / σ(F): 1.37 / Phase error: 30.68 / Stereochemistry target values: ML

	Rfactor	Num. reflection	% reflection
Rfree	0.2633	2343	4.89 %
Rwork	0.2067	-	-
obs	0.2095	47953	63.9 %

• Solvent computation: Shrinkage radii: 0.9 Å / VDW probe radii: 1.1 Å / Solvent model: FLAT BULK SOLVENT MODEL

Refinement step

Cycle: LAST / Resolution: 3.04→88.11 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	26621	0	477	0	27098

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.002	27560
X-RAY DIFFRACTION	f_angle_d	0.464	37559
X-RAY DIFFRACTION	f_dihedral_angle_d	11.191	9887
X-RAY DIFFRACTION	f_chiral_restr	0.041	4313
X-RAY DIFFRACTION	f_plane_restr	0.003	4931

LS refinement shell

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Refine-ID	% reflection obs (%)
3.04-3.11	0.6811	11	0.3715	307	X-RAY DIFFRACTION	7
3.11-3.17	0.3322	27	0.3291	590	X-RAY DIFFRACTION	14
3.17-3.25	0.3867	38	0.3067	876	X-RAY DIFFRACTION	21
3.25-3.33	0.3618	66	0.3072	1124	X-RAY DIFFRACTION	27
3.33-3.42	0.3222	67	0.2788	1410	X-RAY DIFFRACTION	33
3.42-3.52	0.3208	82	0.2875	1711	X-RAY DIFFRACTION	41
3.52-3.63	0.2846	123	0.2675	2056	X-RAY DIFFRACTION	49
3.63-3.76	0.334	129	0.2534	2389	X-RAY DIFFRACTION	57
3.76-3.91	0.3375	143	0.2154	2745	X-RAY DIFFRACTION	66
3.91-4.09	0.3195	186	0.2082	3320	X-RAY DIFFRACTION	79
4.09-4.31	0.2536	206	0.1935	3860	X-RAY DIFFRACTION	93
4.31-4.58	0.2448	195	0.18	4179	X-RAY DIFFRACTION	99
4.58-4.93	0.1961	208	0.1716	4190	X-RAY DIFFRACTION	100
4.93-5.43	0.2752	216	0.1846	4222	X-RAY DIFFRACTION	100
5.43-6.21	0.2674	191	0.2174	4227	X-RAY DIFFRACTION	100
6.21-7.82	0.2441	216	0.2033	4204	X-RAY DIFFRACTION	99
7.83-88.11	0.2173	239	0.1859	4200	X-RAY DIFFRACTION	97

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	1.2505	-1.0682	-0.7599	1.6824	0.4314	0.5181	0.0298	0.1371	-0.4638	-0.1118	0.1613	0.6663	0.0817	-0.4834	0.1806	0.1239	-0.0638	0.0059	0.8229	0.2334	0.51	-17.0524	-8.7081	62.0278
2	2.1529	-1.5417	-0.5305	2.2024	1.2573	2.2205	0.0737	-0.4106	-0.5777	0.1489	0.1708	0.0601	0.2341	0.4069	-0.1	0.2856	0.0306	0.0171	0.9043	0.3759	0.7374	-15.9669	-8.4618	56.2083
3	6.0779	2.4347	0.7699	4.2466	0.6526	2.3267	-0.1848	-0.043	0.1471	-0.053	0.5173	0.9407	0.2913	-0.4084	-0.2321	0.5647	-0.1577	-0.0056	0.6925	0.1476	0.684	-17.0231	-3.33	54.0459
4	2.8191	-1.2572	-0.2568	2.7466	0.1749	3.2864	-0.1659	0.0331	0.0829	0.0396	0.2846	-0.616	0.6773	0.1322	-0.1969	0.4648	0.0185	-0.0278	0.5497	-0.0651	0.4865	2.5547	-12.093	47.8574
5	5.6198	2.2433	-0.0482	1.1508	-0.0989	1.0971	-0.1749	-0.2679	0.1942	-0.0997	0.2786	0.248	0.0335	-0.4958	-0.0402	0.2156	-0.0292	-0.0482	0.3635	-0.0386	0.4884	-3.4379	-8.1582	39.4143
6	0.2798	0.1481	0.0122	0.4608	0.2971	0.2215	0.1266	0.4355	-0.0858	-0.0849	0.1802	0.0811	0.1027	-0.0315	0.0877	0.1978	-0.0866	-0.2753	0.6418	0.2191	0.4341	-6.5592	-10.5333	36.737
7	9.2268	9.1287	4.9715	9.5141	5.6066	3.6537	0.2013	-0.2985	-1.164	-0.2447	-0.1635	-1.6957	0.268	0.3727	0.1913	0.7492	-0.258	0.3363	0.5559	0.0974	0.9787	22.0877	-6.5566	43.3058
8	5.5002	0.4272	-1.3669	3.4402	2.2598	4.8052	0.4745	-0.0658	0.5987	-0.0626	-0.4005	-0.04	-0.6085	0.0554	-0.0294	0.3396	0.0417	0.0246	1.0447	-0.012	1.2108	19.9871	17.9477	46.8018
9	0.0543	0.0463	0.1021	0.0407	0.0885	0.1933	-0.1601	0.2915	-0.0659	-0.0741	0.1408	-0.0009	-0.0318	-0.011	-0.0672	0.5828	0.232	0.2852	1.1107	0.4334	0.7082	18.7332	10.5335	35.1409
10	0.2064	-0.242	-0.1845	0.8086	-0.9212	2.6796	0.0925	-0.6389	0.036	0.495	-0.0638	-0.2856	-0.5453	-0.0786	0.274	0.4166	0.0335	-0.1877	0.8101	-0.2988	0.4573	17.1299	9.4886	55.316
11	1.3653	-0.2666	-0.0465	0.1077	-0.2526	1.2328	-0.0166	1.0165	-1.2757	-0.5211	-0.5775	-0.3771	-0.1778	0.5077	0.5732	1.0379	-0.1714	-0.0118	1.4196	-0.1623	1.3735	27.7245	5.146	38.2174
12	2.3794	-0.9691	-1.4096	0.8488	0.3119	1.2677	0.2416	-0.3964	0.1368	0.1891	0.1563	-0.5188	0.3086	0.2166	0.1603	0.4734	0.007	-0.3745	0.8929	-0.1624	0.7641	15.9516	6.8317	54.805
13	1.9659	0.0274	0.4267	1.7321	0.4284	0.8505	0.1318	-0.1883	0.351	-0.0595	-0.0956	-0.3551	-0.0205	-0.0705	-0.0624	0.2669	0.1392	-0.0767	0.6705	-0.064	0.7115	7.9022	19.2584	42.3901
14	1.3201	-1.7536	-0.1327	5.7953	-0.6879	0.2307	-0.3971	-0.5917	-0.3152	0.7745	0.3817	-0.2724	-0.1076	0.3688	-0.3098	0.4825	0.2461	0.047	0.6075	-0.1528	0.4928	5.8718	17.5303	52.2028
15	0.1353	-0.4716	0.0696	2.8954	-0.1493	0.0438	-0.0421	-0.0833	-0.0483	0.8363	-0.0543	0.7138	0.0605	-0.2397	-0.2039	0.4368	-0.0818	0.1834	1.0209	0.0724	0.3754	-3.8333	22.1417	58.948
16	1.9172	0.4688	0.4477	2.927	-0.6859	2.248	-0.0779	-0.0123	0.1027	0.3824	0.118	0.421	-0.1938	-0.1369	0.0321	0.2684	0.0357	0.1072	0.6685	0.008	0.6795	-6.7796	13.3412	42.1626
17	3.3308	2.3607	0.1114	1.9292	-1.2178	6.6006	0.4688	0.2474	0.6879	-0.2049	0.3961	1.3315	0.0421	-0.6009	-0.5518	0.522	0.077	-0.1039	0.6928	0.1539	0.7969	-19.5673	2.1909	41.6337
18	1.6727	-0.342	1.2355	1.9299	0.6274	1.8812	-0.0646	-0.1362	0.1073	0.0917	0.0094	0.0135	-0.0246	-0.0878	-0.2449	0.2319	-0.2191	0.0214	0.2573	-0.1301	0.0247	-85.685	8.7614	61.5397
19	1.9368	-1.7526	-0.4822	1.6108	0.1229	3.862	0.1262	-0.0946	0.1827	-0.0161	-0.0429	-0.0548	-0.14	0.4781	-0.21	0.2033	-0.0499	0.1241	0.2168	-0.15	0.2523	-75.4138	24.7084	61.8496
20	0.0152	0.0031	-0.0095	0.0527	0.0103	0.1659	-0.0077	-0.0226	-0.0438	-0.0143	0.0544	-0.019	0.0778	0.0286	0.5348	0.1319	0.0912	0.2496	0.0215	0.0395	0.2097	-83.4736	8.8891	52.3396
21	0.1545	0.1144	0.0124	0.3459	-0.042	0.0088	0.0712	0.0007	-0.0215	0.1053	-0.0278	0.14	0.0715	-0.1258	0.4925	0.1134	-0.0997	0.1064	-0.0811	-0.164	-0.0558	-75.7108	18.2917	55.3989
22	1.3772	1.0202	-0.2063	0.7649	-0.0439	1.3332	-0.1588	0.1496	-0.2048	0.0128	-0.0266	0.0442	0.3077	-0.1905	0.2188	0.2618	-0.0343	-0.1545	0.06	-0.1105	0.2505	-62.9823	1.0873	46.5576
23	0.0231	0.0113	-0.0157	0.0097	-0.0229	0.0692	0.0259	-0.0389	-0.0601	0.0009	-0.0721	0.0057	0.0255	0.1047	-0.1368	-0.1269	-0.092	0.137	-0.1816	0.3697	-0.4826	-58.2473	12.121	46.6137
24	0.356	-0.0637	0.0153	0.294	-0.4319	0.6758	-0.0947	0.0531	-0.0376	-0.1119	-0.1323	-0.152	0.0883	0.1881	-1.1152	0.2979	-0.1524	0.2511	0.1774	0.0031	0.0825	-66.7711	15.1303	39.6131
25	-0.0054	0.0033	-0.0024	0.0022	0.0187	0.0209	-0.0548	0.0743	-0.1233	-0.0145	0.0095	-0.1203	0.0497	0.0146	-0.4328	-0.2611	-0.0753	0.274	-0.2533	-0.4429	-0.1634	-69.2073	12.9014	36.6753
26	3.4067	-1.4274	0.5968	0.6814	-0.5801	1.4141	-0.2423	0.0244	0.1847	0.3879	0.054	-0.2947	-0.1078	0.2645	-0.0121	0.8254	0.5385	-0.1748	0.9617	0.1161	1.4103	-41.06	14.8756	43.5865
27	0.85	-0.0823	1.0274	2.0863	0.5238	1.4362	0.7464	0.2328	0.5124	-0.4882	0.1237	-0.9555	-0.4755	-0.1968	-0.5874	0.7935	-0.1787	0.3684	1.2298	0.1502	1.0153	-42.9979	37.4487	43.2496
28	3.9457	1.3469	2.7155	2.752	1.4089	4.0709	0.0229	-1.2138	0.8295	0.5843	-0.2167	-0.2813	-0.1917	-0.4046	0.5704	0.3898	0.0356	-0.282	1.3342	-0.242	1.0697	-47.7523	34.0667	53.4438
29	1.7314	-0.0413	-0.843	3.5629	-2.3734	2.0254	-0.114	0.1585	-0.465	0.4745	-0.0838	-1.0095	-0.5164	0.7531	0.3092	0.4911	-0.163	-0.1274	1.2426	-0.1754	1.2072	-40.7428	28.4011	49.2976
30	0.6749	0.4385	-0.1466	0.7247	0.8171	2.2987	-0.281	0.14	-0.0589	0.1287	0.2004	0.2505	0.1722	0.102	0.0488	0.9225	-0.2844	0.3765	1.4607	0.366	2.0291	-35.8024	37.3921	44.0515
31	2.0046	0.5662	-0.8408	2.7848	-0.216	2.9156	-0.4152	-0.4071	-0.4351	0.4663	0.5287	-0.9919	-0.3968	1.1189	-0.1614	0.6715	-0.1322	-0.3623	0.8754	0.0732	0.9019	-49.6217	27.8465	56.3514
32	0.4346	-0.2861	-0.0777	0.199	0.0492	0.0156	-0.0128	-0.2282	0.1089	0.0758	0.0928	-0.0476	-0.0518	0.0892	0.9182	0.3202	-0.1311	-0.0482	0.0975	-0.1981	-0.2724	-56.8312	44.9815	47.3774
33	0.623	0.559	-0.3047	0.6017	-0.507	0.7089	0.2513	-0.1633	0.1648	0.2437	-0.0438	0.1574	-0.1309	-0.1627	0.7639	0.0572	-0.2064	0.0706	0.2852	0.0677	-0.0321	-62.4386	41.2321	54.0497
34	0.0015	0.0036	-0.0075	-0.0005	-0.003	0.044	-0.0603	-0.0041	0.2081	-0.0193	-0.2193	-0.0129	-0.0622	-0.0527	-1.4269	-0.1229	-0.1198	0.026	-0.3169	-0.1214	0.1141	-76.16	31.0041	41.854
35	3.6507	-0.4057	-0.553	2.2321	0.6191	3.1643	-0.7417	0.3104	-0.0117	-0.2493	0.1915	0.2708	-0.5364	0.23	0.3692	0.5005	0.0222	-0.1881	1.1628	0.288	0.698	-15.9819	56.9183	9.1146
36	4.4585	-2.0866	0.1027	2.9956	0.0642	0.0827	0.1863	1.0015	0.3039	-0.7782	0.3131	0.4	0.0385	-0.2589	-0.0061	0.4253	-0.0735	-0.108	0.8625	0.2929	0.5568	-14.9171	54.9346	16.0798
37	3.0757	2.0319	-0.383	2.365	0.145	0.2029	0.172	-0.0033	0.2698	-0.2279	0.1854	0.5265	-0.0815	-0.221	-0.2339	0.6093	-0.327	-0.1246	0.7947	0.4156	0.9462	-0.1849	68.9655	22.5038
38	2.1912	-0.2584	-0.7744	1.3758	0.6371	2.7621	0.3985	0.4235	-0.1463	-0.1464	0.221	-0.381	-0.2254	0.1147	-0.3696	0.3299	-0.1388	-0.0445	0.6225	0.0462	0.6562	3.4734	58.743	27.1053
39	1.3084	-0.0019	-0.1921	0.1493	-0.0456	0.2414	0.0206	-0.0513	0.2001	0.0182	0.0346	0.1001	-0.0317	0.0515	0.0743	0.1731	0.0937	-0.0885	0.6312	-0.2387	0.7197	-6.2926	60.867	40.0724
40	0.0708	0.2788	0.1679	1.5974	-0.3192	2.3946	-0.2066	0.2929	0.1648	-0.2401	0.4117	-0.4849	-0.3473	0.3016	0.0999	0.4404	-0.0646	-0.1361	0.4808	0.0213	0.6596	1.0135	58.2121	29.7933
41	4.1091	1.3968	-1.2741	1.5876	0.1654	5.2369	0.3421	0.2739	0.7192	0.0883	-0.224	-0.7323	0.5765	0.3171	0.1728	0.6463	0.1016	0.1783	1.1347	-0.3161	1.4546	21.2985	35.6009	28.3513
42	2.4793	-0.1739	-1.0161	3.4337	-0.6273	3.4916	0.4808	0.0593	0.6285	-0.3847	0.678	-0.1399	0.6398	-0.3387	-0.8941	0.5932	-0.1372	-0.004	1.4963	-0.075	0.6708	16.4191	38.9533	16.8207
43	4.4827	0.0941	-0.205	0.3213	-0.5333	0.9033	0.2042	-0.074	0.9204	-0.0966	0.0137	-0.4974	-0.2461	0.3695	-0.5398	0.4141	0.1975	0.2265	0.9145	-0.1504	1.3153	24.0677	43.0447	27.0899
44	2.3153	1.8915	0.2688	2.8962	-0.2996	0.2382	-0.1161	0.4962	-0.209	-0.1891	0.1293	-0.3783	0.1098	0.5809	-0.1428	0.9609	0.382	-0.1134	1.805	-0.4289	1.5628	27.3656	36.9115	33.1261
45	1.8609	0.2873	0.4315	1.9139	1.0732	2.3809	0.1903	-0.011	-0.175	-0.0394	0.3272	-0.7118	-0.1578	0.0948	-0.3063	0.7364	0.3914	-0.22	1.9207	-0.2284	1.9848	29.9972	40.5896	22.5645
46	2.2238	2.4656	1.5565	6.4268	-0.0641	6.4015	-0.0303	-0.3408	0.5882	-0.2979	0.2316	-0.3993	0.1319	0.9354	-0.2248	1.2132	0.3849	-0.1023	1.0089	-0.0553	0.8489	19.3449	46.7339	16.9648
47	3.7426	-0.2576	0.0528	3.1946	1.2598	8.7512	0.6852	0.7013	0.1115	-0.7734	0.1334	-0.1823	-0.8762	-0.7084	-0.5682	0.6234	0.1193	0.2247	0.6439	-0.1077	0.9152	4.6672	37.7477	17.6026
48	1.4642	1.782	0.9452	2.3306	0.6531	2.0299	0.1626	0.1863	-0.0034	-0.2238	-0.0369	-0.6965	0.0072	0.392	-0.1236	0.5626	0.2466	0.0623	0.8662	-0.1935	0.6953	6.8358	29.6683	22.4365
49	1.308	0.9241	-2.6034	4.6792	-4.2081	6.5745	-0.4728	0.8882	0.5259	-0.7147	-0.3193	0.1758	0.0114	-0.5871	0.4052	0.7161	0.081	-0.0927	0.7893	0.175	0.5286	-4.4841	26.365	13.0088
50	0.3808	-0.8111	-0.3263	1.7669	0.9664	2.2368	-0.1773	-0.0198	-0.4776	0.0714	0.094	0.243	0.3709	0.3389	0.3547	0.2653	0.0954	0.1241	0.4222	-0.1804	0.6578	-0.5292	28.9848	31.136
51	1.1841	-0.0107	0.2288	1.2154	-0.067	2.2839	0.2116	0.3937	-0.3195	-0.2423	-0.1546	0.3506	0.6426	-0.4459	-0.0765	0.5985	-0.1142	-0.0664	0.575	-0.086	0.3965	-13.5716	42.2573	29.7449
52	0.3668	0.0005	0.0776	0.0486	0.039	0.2139	-0.1689	-0.2103	0.1531	0.0545	-0.0003	-0.065	-0.2375	-0.1528	-0.586	0.8896	0.0518	-0.4488	0.8223	0.3189	0.6269	-85.3115	86.8547	10.3217
53	0.2055	-0.1092	0.2735	0.0511	-0.1259	0.7313	-0.1305	-0.0649	0.1012	0.0318	0.0533	0.0084	-0.2872	-0.1068	-0.471	0.5677	-0.2782	-0.24	0.4193	0.1556	-0.0673	-76.5807	76.824	12.1179
54	0.4026	0.0735	0.2531	0.2061	0.3641	0.7782	-0.1271	-0.0478	0.1887	-0.0725	-0.1476	0.0073	-0.2887	0.0009	-0.4556	0.4992	-0.2802	-0.2715	0.5117	0.1423	0.2383	-79.2144	76.3844	18.7584
55	0.5983	-0.2078	0.4647	0.3241	-0.0836	1.6108	-0.0551	0.0851	0.0392	-0.0873	-0.0007	0.0541	-0.1315	-0.0551	-0.3423	0.8831	-0.2863	-0.3282	0.5939	0.0984	0.2368	-77.177	77.833	14.8284
56	0.0102	0.0144	0.0196	-0.0001	0.0015	0.0207	-0.1915	0.1463	0.0373	-0.1822	0.0817	0.0424	-0.1107	-0.0705	0.1313	0.6007	-0.4181	-0.1127	0.0483	-0.1248	-0.0667	-57.7023	82.8483	25.4099
57	4.0649	-0.3261	0.2878	5.4164	-0.5605	2.7819	0.0851	-0.0947	-0.0463	0.5492	0.1941	0.4399	0.103	-0.2801	-0.0007	0.1559	-0.0327	-0.0069	0.1485	0.1107	0.3676	-61.1977	79.2096	34.4093
58	0.7887	0.2237	-0.15	0.8023	0.2971	0.4403	0.0329	0.204	0.1307	-0.2496	0.0935	0.3093	0.0374	-0.2897	0.5427	0.0361	-0.0837	-0.0924	0.234	0.0405	0.111	-70.7009	83.0996	33.6117
59	2.5721	0.8952	-1.6678	0.7659	-1.9637	5.2904	-0.3151	-0.4575	-0.7364	-0.2678	0.3167	-1.9973	-0.1157	1.4104	-0.0745	0.4019	-0.1959	0.006	0.737	0.0268	1.3046	-41.5986	82.6383	29.796
60	2.4843	-0.7165	0.0444	1.2662	-0.2928	3.5551	0.0512	-0.4028	-0.7362	0.0704	-0.1284	0.0786	0.2009	0.571	-0.0773	0.1426	0.0847	0.0194	0.4603	0.1422	0.3408	-42.2222	58.1543	27.3476
61	0.5225	-0.1579	-0.2517	0.2225	-0.0155	0.2683	-0.0012	-0.2182	0.0809	0.0082	-0.0192	-0.0165	-0.0107	0.066	-0.0141	-0.0758	0.0643	0.083	0.172	-0.1638	0.1139	-47.1621	62.0082	19.4913
62	3.6604	2.0678	1.3158	2.5826	0.6245	1.5132	-0.0913	0.2845	0.2922	-0.3266	0.3063	0.1023	-0.0072	0.091	0.6522	0.1542	-0.1701	0.015	0.4145	-0.2556	0.2837	-42.0843	65.4424	21.1367
63	0.5982	-0.7467	0.4378	1.1718	-1.1319	1.6968	0.22	0.1845	0.2523	0.1552	-0.177	-0.8312	-0.0539	0.6299	-0.1799	0.1628	0.0178	-0.1035	0.3332	-0.1793	0.7163	-37.0329	65.3356	26.5548
64	0.4873	0.2359	-0.2863	0.6753	-0.4916	0.9762	0.0648	0.1685	-0.0644	-0.1832	0.046	-0.0101	0.0914	-0.0953	0.8509	0.2153	-0.1872	0.024	0.3209	0.0885	-0.0273	-57.9359	61.926	17.5228
65	-0.0031	0.0108	-0.0192	0.0494	-0.0321	0.2039	-0.0761	0.0582	-0.0277	-0.0421	0.0047	0.0092	0.1009	-0.0381	-0.5905	0.1197	-0.2233	-0.0325	-0.2463	0.0173	-0.2521	-56.0537	52.8438	23.3996
66	0.8659	0.1665	-1.046	0.7194	-0.9435	2.066	-0.0898	-0.0168	-0.1459	-0.1729	0.1802	0.2091	0.5825	-0.497	-0.1188	1.0145	-0.4294	-0.0859	0.7453	0.149	0.3576	-65.3043	51.3658	8.0138
67	0.0376	0.0355	-0.0009	0.0433	-0.0168	0.0732	-0.0169	0.0556	-0.0136	-0.1157	0.0445	0.0174	0.0405	-0.0344	0.1807	0.2834	-0.3899	-0.0751	0.1988	0.0325	0.0387	-66.3329	50.1665	21.9831
68	0.3369	0.2142	-0.2131	0.2474	-0.2275	0.3365	0.1916	-0.0353	0.1817	-0.1215	0.0658	0.2888	0.0751	-0.3252	0.5244	0.0794	-0.1562	0.0437	0.0869	0.1894	0.0783	-76.7579	65.0388	29.876
69	1.9154	0.0929	0.0655	7.4195	3.5138	2.3664	-0.0765	0.3143	-0.0715	0.3149	-0.2267	0.7076	0.2064	-0.0014	0.1608	0.7868	-0.0999	-0.1071	0.9585	0.3401	0.7422	-18.1511	10.9836	3.0673
70	3.6649	0.694	-1.7408	9.3773	0.2541	2.5336	-0.1527	1.1246	-0.3277	-0.7239	0.0625	0.6652	-0.0729	-0.0538	0.1387	0.4444	-0.2777	-0.2134	1.0873	-0.0733	0.7585	-11.4217	-2.1155	2.5028
71	2.6719	1.3119	0.7806	2.5643	0.6737	2.6288	-0.0568	0.533	0.376	-0.0015	0.2803	0.2487	-0.0999	-0.1357	-0.3034	0.59	0.0792	-0.1645	0.8993	0.2122	0.5326	-15.5301	3.9709	9.8857
72	3.2074	-1.7396	-0.3522	4.1995	1.2177	0.3599	0.2934	0.3551	-0.6644	-0.4618	-0.0499	0.5985	0.5312	-0.9186	-0.107	0.7073	-0.261	-0.1909	0.89	0.0288	0.528	-13.9722	-2.1799	10.1379
73	2.512	1.4373	0.0553	2.3339	0.6336	2.0621	-0.2816	0.2823	-0.5901	-0.0239	0.07	-0.401	0.2802	0.2005	0.1267	0.2542	-0.0595	0.0532	0.6285	-0.0636	0.5251	5.3066	3.7445	17.8639
74	4.1768	-1.5913	0.6843	3.7248	0.4088	0.9295	-0.2377	-0.3767	-0.2362	-0.1149	0.3526	-0.2029	0.0742	-0.247	0.0095	0.2271	-0.054	-0.006	0.7225	0.1236	0.2749	-3.2674	3.4936	26.8747
75	1.8555	0.1892	0.5794	1.3825	0.2042	0.2274	0.0186	0.1077	0.0806	0.0773	0.2387	-0.494	0.1704	-0.1148	0.3169	0.2261	-0.1527	-0.1137	0.74	0.02	0.3619	0.7921	2.2409	27.3892
76	2.7749	0.2945	-0.2239	4.6001	-1.9691	3.1294	0.1464	-0.4837	-0.4768	-0.3758	0.0024	-0.9792	1.0744	0.77	-0.0714	0.8646	0.1105	-0.08	0.9821	-0.0637	0.7648	13.7236	-23.062	15.9173
77	2.3443	-2.342	1.0628	5.6	-3.4007	4.1753	-0.2778	0.435	-0.407	-0.2917	-0.2929	-0.3472	0.4226	0.6973	0.2575	0.4869	-0.1362	0.2161	1.2602	-0.4311	0.7245	17.6287	-19.0895	1.3423
78	7.2483	0.1224	-0.0061	1.9544	-2.6757	3.8363	-0.2058	-0.1517	0.5341	-0.5055	0.1481	-0.4603	-0.1576	-0.2765	0.0091	0.8501	0.4523	-0.0942	0.9281	-0.2143	1.0434	16.5507	-19.182	17.649
79	1.0582	0.1118	0.3702	5.3068	2.2083	2.6184	0.5305	-0.4201	-0.5797	0.0439	0.0781	-0.8168	0.5188	0.3862	-0.7136	0.6475	0.2544	-0.1315	1.4994	0.0168	0.9516	23.6104	-23.4612	25.1449
80	1.1284	-0.1756	0.3521	0.0695	-0.1507	0.3331	0.1688	-0.2191	0.3281	-0.5315	0.6263	-0.5774	-0.1132	0.4547	-0.6056	1.6976	-0.1735	-0.1895	1.3483	-0.0735	1.5679	26.2265	-22.7103	15.83
81	2.0474	-0.5048	0.2554	2.4248	-1.8596	4.448	-0.0999	0.107	-0.3176	0.3819	0.641	-0.1367	-0.0748	0.1694	-0.4053	0.743	-0.0326	-0.0167	0.6054	-0.1066	0.6869	7.0989	-18.8284	13.3372
82	1.6093	-0.1453	0.7254	1.0293	-0.5326	2.2059	-0.5307	0.1985	0.1934	-0.5344	0.1022	-0.5	0.964	-0.2504	0.4794	1.0384	-0.4742	-0.0653	0.9271	0.0877	1.057	-0.1019	-25.9773	11.8503
83	4.1432	-1.5471	2.0696	1.15	0.015	2.119	-0.0135	-0.083	0.1035	0.108	-0.266	-0.0268	0.3697	-0.7607	-0.1189	1.0553	-0.1087	-0.3685	0.9835	0.1011	0.4561	-10.8704	-27.5362	7.4498
84	0.6838	-0.3029	-0.3534	3.4122	-1.693	1.7406	0.3746	-0.5286	-0.7316	-0.6089	-0.5127	-0.152	0.6988	-0.0571	-0.0318	0.7508	-0.0713	-0.2188	0.8652	0.1574	0.597	-9.8448	-18.9452	22.1484
85	0.0085	0.1007	0.049	0.9413	0.4454	0.211	0.0004	0.0826	-0.2469	-0.2936	0.0299	0.4803	-0.0275	-0.1698	0.2046	0.4547	-0.2555	-0.1211	1.0189	0.0895	0.5243	-20.1678	-5.7833	24.7912
86	0.0388	-0.0116	0.0929	0.0026	-0.0273	0.2188	0.0231	-0.0434	-0.006	-0.0025	0.026	0.0566	0.0827	-0.0739	-0.3397	0.6987	0.1181	0.0661	0.355	0.3267	0.3777	-84.9919	37.923	6.4796
87	0.2283	-0.138	0.1812	0.3525	0.1244	1.2533	0.038	0.0408	0.0084	0.0062	-0.0384	-0.0086	0.1202	0.1757	0.0629	0.5451	-0.1943	-0.1966	0.5861	0.2202	0.1896	-76.9401	29.0466	0.2611
88	0.3252	-0.2258	0.256	0.4646	-0.7737	1.4385	0.0697	0.2026	-0.0052	-0.3572	0.0551	0.0145	0.3509	-0.2032	0.1581	0.5363	-0.1548	0.0234	0.1992	0.158	0.1583	-75.6318	22.7077	6.6208
89	0.0372	-0.0208	-0.0096	0.3066	-0.1333	0.0832	0.0938	0.0519	0.1652	-0.2773	0.1446	0.0666	-0.2249	-0.0751	1.9052	0.3874	-0.1017	0.1301	-0.6821	0.1292	-0.2299	-64.7458	26.0432	16.3998
90	0.2888	-0.1803	-0.1509	0.7012	0.5177	0.4945	-0.0434	0.0166	-0.1197	0.0193	0.0145	-0.0382	0.0599	0.0236	0.1051	0.2557	0.1591	0.2246	-0.1794	-0.1958	0.047	-69.2046	29.7961	27.0534
91	0.1264	-0.1157	-0.1239	0.1244	0.085	0.129	0.0093	-0.0131	0.1375	-0.0327	0.066	-0.129	-0.0441	0.0327	-0.0773	-0.1307	0.1476	0.1182	0.0093	-0.1203	-0.119	-67.7236	26.3534	28.3927
92	3.1538	-1.4908	-3.0387	0.7468	1.5862	3.4546	-0.0201	0.1304	-0.0476	-0	0.1597	-0.1237	0.0329	0.2269	-0.105	0.4476	0.1366	0.3413	0.6404	-0.0359	1.2721	-41.713	20.7833	23.0586
93	5.6023	-0.9196	1.9114	1.2119	-0.591	5.387	0.5882	-0.336	-0.7494	0.0671	0.3808	-0.7277	0.8613	0.1143	-0.5671	0.6526	0.1624	0.0249	0.4921	-0.1092	0.6812	-48.6336	-0.7288	20.1883
94	0.2034	-0.2932	-0.231	0.8867	0.1411	0.3375	0.0737	0.0148	0.0743	0.0001	0.0783	-0.1731	0.0344	0.116	0.1325	0.4638	0.2802	0.0579	0.2719	-0.2651	0.3337	-47.63	4.6343	11.0419
95	1.5359	-0.2582	-1.5298	0.9702	-0.6868	2.4827	-0.2681	-0.6063	0.1677	0.2267	0.3835	-0.4244	-0.1871	0.4413	-0.7172	0.946	0.3342	0.1439	0.6482	-0.3429	1.1136	-40.2278	-1.3624	24.4082
96	0.9758	-0.4559	0.1597	6.4088	2.8189	1.4261	0.1461	0.4745	-0.2283	-0.7231	0.1792	-0.0099	0.227	0.1427	-0.0831	1.0702	0.3945	-0.2966	1.826	-0.2807	1.4651	-36.6567	4.329	14.9088
97	0.0891	-0.0588	-0.0288	0.0967	0.0784	0.2098	-0.04	0.1418	-0.0381	-0.0615	-0.0746	0.0916	0.1473	-0.0713	-0.4803	0.2955	-0.0937	-0.0048	0.0542	-0.2551	-0.0278	-57.5292	3.9729	13.2464
98	0.1061	0.0047	0.154	0.1895	-0.1449	0.5881	0.0261	-0.0874	-0.0321	0.019	0.0521	-0.0452	0.2091	-0.0151	0.2663	0.4455	0.1026	-0.042	0.0764	0.1215	-0.1549	-63.531	-2.7869	12.2892
99	0.1771	-0.3222	-0.3078	1.1676	1.2053	2.1879	-0.2555	0.2375	0.0371	-0.4051	0.0142	0.0929	-0.3675	-0.0743	0.1116	0.6484	-0.3323	0.0872	0.3903	-0.1439	0.2071	-75.4624	-4.6384	3.4687
100	1.1462	0.8289	0.0806	1.264	-0.8358	3.8751	-0.0876	0.1206	0.043	-0.1256	0.1247	0.0548	-0.0518	-0.0558	-0	0.3658	-0.2706	0.0163	0.3241	0.0078	0.0943	-72.4824	-3.1147	16.3168
101	0.019	-0.0211	0.0139	0.0096	-0.0111	0.008	0.0202	-0.0732	-0.1248	0.0131	-0.0552	0.0793	0.0736	-0.0387	-0.2683	0.0242	-0.2553	-0.0875	0.081	-0.0493	0.1029	-75.8093	6.4052	24.3985
102	0.4589	-0.3825	0.1459	0.6159	0.3899	0.9289	-0.0745	0.0345	-0.1105	-0.1369	0.011	0.1622	0.0472	-0.1447	0.2367	0.1032	-0.0774	-0.0435	0.0932	-0.0011	0.1408	-83.5885	19.943	22.1867
103	1.3454	-0.2224	-1.1042	3.6611	1.2484	3.8502	-0.1294	-0.476	-0.3352	1.0891	-0.2328	0.7272	0.4031	0.2816	0.4954	0.6154	-0.1997	0.1978	0.8604	0.2752	0.6311	-24.7081	37.7909	65.4481
104	3.3291	-1.4622	-0.7752	2.572	-0.393	5.3634	-0.0511	-0.912	0.1906	0.3654	0.5507	-0.3123	-0.7904	-0.5794	-0.3485	0.4248	0.0463	-0.125	0.7873	0.0135	0.5358	-13.7909	48.3179	68.0927
105	3.2599	0.2842	0.1481	5.5816	0.5592	2.7921	-0.1323	-0.1703	-0.3852	0.5251	0.3892	-0.1039	0.2595	-0.5778	-0.3049	0.4959	0.0477	0.1254	0.5464	-0.0388	0.567	-15.3176	45.218	59.1202
106	3.1422	-1.5084	-1.307	3.1466	0.0879	3.8857	0.1165	-0.5408	0.3854	-0.5188	0.0221	-0.7624	0.3234	0.711	0.0189	0.4373	0.0439	-0.0365	0.5661	-0.1107	0.4359	4.0747	42.3826	54.5854
107	0.1004	-0.0573	-0.0874	0.1006	0.0064	0.2319	0.0376	0.0069	0.1194	-0	-0.0469	-0.3381	-0.0079	0.2308	-0.2213	0.0399	-0.054	-0.3142	0.6314	-0.1487	0.8171	-1.3257	47.6265	46.9369
108	0.5487	0.9008	-0.4541	1.6122	-0.137	3.1621	-0.0798	0.0774	0.2575	0.2138	-0.5069	-0.7479	0.3381	0.2593	0.1808	0.4198	-0.0249	-0.1971	1.1837	-0.0345	1.1691	23.4514	58.6045	51.3849
109	2.1835	-0.9116	0.0715	1.9454	-0.5058	0.9223	-0.2974	0.2518	0.3691	-0.6096	0.5711	0.2137	-0.1165	-0.5139	-0.1758	0.8068	-0.3045	-0.4814	1.2866	0.4716	1.8823	16.3475	76.4828	48.12
110	2.9466	-0.2417	1.0973	0.7562	-0.2154	1.3372	0.0463	-0.3148	0.377	0.1476	-0.0339	-0.0464	-0.0153	-0.0368	-0.1193	0.3134	-0.0822	-0.2755	0.9854	-0.1051	0.8665	15.0646	66.3125	48.3462
111	3.9732	0.1982	0.6924	0.4492	-0.4349	0.6227	0.0389	-0.317	0.0348	0.0812	-0.1357	0.0977	-0.0676	-0.1143	0.0204	0.4563	-0.2394	-0.1553	1.153	-0.2463	1.1344	18.5122	66.7518	52.3235
112	4.7585	0.4614	-0.1488	2.0084	-1.0428	3.5125	-0.3093	0.0273	-0.4301	-0.3493	-0.0037	-0.648	-0.7619	0.1354	0.2967	1.3065	-0.2491	-0.3745	1.9246	0.0681	1.2805	26.2906	65.5732	44.3441
113	1.3692	0.097	-0.237	0.0088	0.0003	0.1738	0.1583	-0.5082	-0.3208	0.0089	-0.1669	0.0396	0.1246	0.4203	-0.4433	0.904	-0.0751	-0.7008	1.4549	0.0342	1.5424	23.9569	67.703	56.5717
114	1.6282	-0.6628	0.2824	1.0449	-0.3844	0.1422	-0.412	-0.1352	-0.1246	0.0725	-0.1992	0.224	0.5591	-0.3491	0.5219	1.4105	0.6704	0.1583	1.594	-0.0808	0.9713	6.0813	64.9082	66.9756
115	0.6833	-0.15	0.5972	0.2358	-0.2364	1.523	0.2417	-0.1572	0.0311	-0.0241	0.2436	-0.0947	-0.1577	-0.2481	-0.0177	0.2738	0.0865	0.0607	0.5766	-0.0995	1.0697	1.4284	71.4851	50.5035
116	0.6948	-0.3722	-0.8968	2.0436	0.6096	3.1505	0.1803	-0.2319	-0.4025	0.4693	-0.1188	-0.4472	-0.099	0.0732	-0.1631	0.6122	-0.0942	-0.0016	1.0549	-0.3571	1.2154	2.0721	77.9488	56.1215
117	6.5566	-2.7659	-0.1319	4.6539	0.2711	1.8463	-0.6369	-1.3895	-0.5399	1.2224	-0.3175	1.4398	-0.235	-0.7763	0.7127	0.9077	0.1341	0.23	1.1846	-0.084	0.9806	-5.8647	74.5315	63.7079
118	1.138	1.5324	0.0451	3.1354	-1.2312	1.5622	0.2776	0.2331	0.4192	0.1939	-0.213	0.3552	-0.1774	-0.2435	0.0726	0.3905	0.2246	-0.0969	0.7109	-0.0997	0.5991	-13.8934	62.4079	47.9335
119	0.051	-0.0581	-0.1085	0.0635	0.1279	0.2528	0.0322	-0.1796	0.2196	0.0495	0.0779	0.064	-0.0512	-0.1124	0.6484	0.1821	0.1385	0.3173	0.0795	-0.1499	-0.1265	-78.3842	67.8537	65.8266
120	0.3889	0.0014	0.0502	1.4031	-0.1293	0.191	0.2847	-0.2951	-0.494	-0.1924	0.1042	0.3057	0.2808	-0.5581	0.0087	0.4744	-0.1986	-0.1076	1.2849	-0.2028	0.5378	-88.1862	63.3983	56.5206
121	0.0057	0.0069	0.0476	0.0191	0.1093	0.3174	-0.0263	0.0695	0.0127	0.1491	-0.0678	0.1489	-0.0285	-0.222	-0.4251	0.173	-0.0444	0.4154	0.1173	-0.0627	-0.0389	-71.1545	69.4007	59.4414
122	0.0453	0.0134	-0.0081	0.0027	0.0001	0.0016	0.0109	-0.1328	0.0651	0.0841	-0.0272	0.047	-0.0403	0.0416	0.4296	0.1221	0.1212	-0.0067	-0.0376	-0.0279	-0.3844	-56.7661	70.8898	53.3581
123	0.0858	0.0918	-0.0621	0.2108	-0.1318	0.1041	0.0307	0.0968	0.0776	-0.0015	0.1648	0.1422	0.0679	-0.1877	0.8983	-0.1001	-0.2652	0.114	-0.2317	0.1359	-0.2244	-67.2641	68.803	44.1666
124	2.8307	2.3745	1.7307	2.0145	1.5735	1.6167	0.1905	-0.2154	-0.0002	0.1258	0.0908	-0.3581	-0.0201	0.2494	-0.1367	0.1237	0.0177	-0.0111	0.3301	-0.2578	0.3637	-41.7116	75.1342	49.2797
125	1.8194	-1.0536	-0.0614	1.35	0.5623	0.8561	0.027	-0.1199	0.4993	0.166	0.0511	-0.0008	-0.5835	0.1472	0.1865	0.3958	-0.0883	-0.0725	0.1069	-0.0534	0.3598	-46.3578	99.4523	48.351
126	4.5405	-2.2869	-1.9307	2.1914	2.1375	6.0614	0.1696	0.0111	0.4818	-0.1291	-0.0285	-0.0832	-0.2387	-0.2227	0.0431	0.2518	-0.0104	-0.1703	0.1351	0.0206	0.7211	-47.9153	90.0391	46.3103
127	2.511	0.6042	1.8108	4.12	-0.7464	2.1796	0.1522	-0.2577	0.6368	0.8039	-0.1521	-0.1747	-0.1377	0.0901	0.4751	0.9787	-0.3348	-0.0211	0.3408	-0.01	0.9747	-47.4696	102.4978	60.4392
128	2.6362	2.6742	0.6537	5.2604	0.8741	2.3207	-0.2111	0.5238	-0.8065	-0.3443	0.5076	-1.109	0.3354	0.3088	-0.8724	0.2496	-0.1427	-0.0972	0.2	-0.0735	0.4714	-39.4914	85.4818	46.7697
129	0.1243	0.3686	-0.0812	1.3013	-0.1517	0.4699	0.0832	0.068	0.283	-0.0583	0.0966	0.03	-0.2377	-0.0103	0.34	0.3657	-0.1854	0.059	0.308	0.1501	0.7165	-38.283	97.0331	47.4201
130	0.3055	-0.1402	-0.0178	0.064	0.0094	0.0921	0.0348	-0.0385	-0.0362	0.0282	-0.0148	0.0913	-0.0116	-0.0628	0.0921	0.144	0.0641	0.0844	0.8094	-0.0309	0.7967	-42.0194	85.2753	59.2674
131	3.1243	-1.2952	-1.2774	3.364	2.6678	2.1396	-0.3678	-0.5259	-0.1007	0.4096	-0.0495	0.4594	0.3457	-0.0674	0.3699	1.872	1.0898	-0.2323	1.917	-0.3497	0.9805	-58.0563	88.4502	68.3034
132	1.9417	0.6261	0.7405	1.4859	1.0419	1.6575	0.21	-0.2761	-0.2109	0.2298	-0.1072	-0.1037	0.1101	-0.0909	-0.1927	0.2169	-0.0521	-0.1754	0.1807	0.0127	0.7746	-61.8638	96.5741	52.6337
133	0.8061	-0.2459	0.777	1.0657	-0.392	0.7744	0.0207	-0.689	0.2969	0.7089	0.3714	-0.0194	-0.3894	-0.0958	-0.1219	0.5408	0.0184	0.1042	0.369	-0.1459	0.2637	-66.0049	99.0267	60.6068
134	0.2877	-0.3747	-0.0733	0.7347	-0.1918	0.3865	-0.0925	-0.027	0.021	-0.0207	0.0401	0.1512	0.0027	0.025	-0.1816	0.3219	0.1372	-0.2522	0.1907	0.1856	0.5004	-73.5828	91.0121	47.9965
135	0.2382	0.3515	-0.4001	0.5952	-0.4339	0.9975	0.0484	-0.0169	0.0032	0.0304	0.0358	0.0488	0.0102	-0.1347	0.3137	0.0512	-0.0498	0.0132	0.312	0.2795	0.0967	-83.4129	77.3948	47.5038

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details
1	X-RAY DIFFRACTION	1	(chain A and resid 3:33)
2	X-RAY DIFFRACTION	2	(chain A and resid 34:56)
3	X-RAY DIFFRACTION	3	(chain A and resid 57:85)
4	X-RAY DIFFRACTION	4	(chain A and resid 86:153)
5	X-RAY DIFFRACTION	5	(chain A and resid 154:174)
6	X-RAY DIFFRACTION	6	(chain A and resid 175:213)
7	X-RAY DIFFRACTION	7	(chain A and resid 214:223)
8	X-RAY DIFFRACTION	8	(chain A and resid 224:236)
9	X-RAY DIFFRACTION	9	(chain A and resid 237:246)
10	X-RAY DIFFRACTION	10	(chain A and resid 247:281)
11	X-RAY DIFFRACTION	11	(chain A and resid 282:301)
12	X-RAY DIFFRACTION	12	(chain A and resid 302:340)
13	X-RAY DIFFRACTION	13	(chain A and resid 341:357)
14	X-RAY DIFFRACTION	14	(chain A and resid 358:382)
15	X-RAY DIFFRACTION	15	(chain A and resid 383:401)
16	X-RAY DIFFRACTION	16	(chain A and resid 402:435)
17	X-RAY DIFFRACTION	17	(chain A and resid 436:460)
18	X-RAY DIFFRACTION	18	(chain B and resid 3:21)
19	X-RAY DIFFRACTION	19	(chain B and resid 22:42)
20	X-RAY DIFFRACTION	20	(chain B and resid 43:63)
21	X-RAY DIFFRACTION	21	(chain B and resid 64:94)
22	X-RAY DIFFRACTION	22	(chain B and resid 95:99)
23	X-RAY DIFFRACTION	23	(chain B and resid 100:152)
24	X-RAY DIFFRACTION	24	(chain B and resid 153:175)
25	X-RAY DIFFRACTION	25	(chain B and resid 176:214)
26	X-RAY DIFFRACTION	26	(chain B and resid 215:221)
27	X-RAY DIFFRACTION	27	(chain B and resid 222:246)
28	X-RAY DIFFRACTION	28	(chain B and resid 247:259)
29	X-RAY DIFFRACTION	29	(chain B and resid 260:294)
30	X-RAY DIFFRACTION	30	(chain B and resid 295:308)
31	X-RAY DIFFRACTION	31	(chain B and resid 309:340)
32	X-RAY DIFFRACTION	32	(chain B and resid 341:366)
33	X-RAY DIFFRACTION	33	(chain B and resid 367:404)
34	X-RAY DIFFRACTION	34	(chain B and resid 405:460)
35	X-RAY DIFFRACTION	35	(chain C and resid 3:33)
36	X-RAY DIFFRACTION	36	(chain C and resid 34:92)
37	X-RAY DIFFRACTION	37	(chain C and resid 93:99)
38	X-RAY DIFFRACTION	38	(chain C and resid 100:175)
39	X-RAY DIFFRACTION	39	(chain C and resid 176:194)
40	X-RAY DIFFRACTION	40	(chain C and resid 195:218)
41	X-RAY DIFFRACTION	41	(chain C and resid 219:243)
42	X-RAY DIFFRACTION	42	(chain C and resid 244:266)
43	X-RAY DIFFRACTION	43	(chain C and resid 271:289)
44	X-RAY DIFFRACTION	44	(chain C and resid 290:303)
45	X-RAY DIFFRACTION	45	(chain C and resid 304:313)
46	X-RAY DIFFRACTION	46	(chain C and resid 314:325)
47	X-RAY DIFFRACTION	47	(chain C and resid 326:346)
48	X-RAY DIFFRACTION	48	(chain C and resid 347:383)
49	X-RAY DIFFRACTION	49	(chain C and resid 384:400)
50	X-RAY DIFFRACTION	50	(chain C and resid 401:410)
51	X-RAY DIFFRACTION	51	(chain C and resid 411:460)
52	X-RAY DIFFRACTION	52	(chain D and resid 3:19)
53	X-RAY DIFFRACTION	53	(chain D and resid 20:56)
54	X-RAY DIFFRACTION	54	(chain D and resid 57:78)
55	X-RAY DIFFRACTION	55	(chain D and resid 79:93)
56	X-RAY DIFFRACTION	56	(chain D and resid 94:158)
57	X-RAY DIFFRACTION	57	(chain D and resid 159:164)
58	X-RAY DIFFRACTION	58	(chain D and resid 165:214)
59	X-RAY DIFFRACTION	59	(chain D and resid 215:219)
60	X-RAY DIFFRACTION	60	(chain D and resid 220:241)
61	X-RAY DIFFRACTION	61	(chain D and resid 242:264)
62	X-RAY DIFFRACTION	62	(chain D and resid 265:284)
63	X-RAY DIFFRACTION	63	(chain D and resid 285:323)
64	X-RAY DIFFRACTION	64	(chain D and resid 324:346)
65	X-RAY DIFFRACTION	65	(chain D and resid 347:380)
66	X-RAY DIFFRACTION	66	(chain D and resid 381:389)
67	X-RAY DIFFRACTION	67	(chain D and resid 390:408)
68	X-RAY DIFFRACTION	68	(chain D and resid 409:460)
69	X-RAY DIFFRACTION	69	(chain E and resid 3:24)
70	X-RAY DIFFRACTION	70	(chain E and resid 25:29)
71	X-RAY DIFFRACTION	71	(chain E and resid 30:63)
72	X-RAY DIFFRACTION	72	(chain E and resid 64:88)
73	X-RAY DIFFRACTION	73	(chain E and resid 89:153)
74	X-RAY DIFFRACTION	74	(chain E and resid 154:180)
75	X-RAY DIFFRACTION	75	(chain E and resid 181:220)
76	X-RAY DIFFRACTION	76	(chain E and resid 221:264)
77	X-RAY DIFFRACTION	77	(chain E and resid 265:273)
78	X-RAY DIFFRACTION	78	(chain E and resid 274:282)
79	X-RAY DIFFRACTION	79	(chain E and resid 283:304)
80	X-RAY DIFFRACTION	80	(chain E and resid 305:311)
81	X-RAY DIFFRACTION	81	(chain E and resid 312:355)
82	X-RAY DIFFRACTION	82	(chain E and resid 356:385)
83	X-RAY DIFFRACTION	83	(chain E and resid 386:401)
84	X-RAY DIFFRACTION	84	(chain E and resid 402:432)
85	X-RAY DIFFRACTION	85	(chain E and resid 433:460)
86	X-RAY DIFFRACTION	86	(chain F and resid 3:14)
87	X-RAY DIFFRACTION	87	(chain F and resid 15:27)
88	X-RAY DIFFRACTION	88	(chain F and resid 28:50)
89	X-RAY DIFFRACTION	89	(chain F and resid 51:158)
90	X-RAY DIFFRACTION	90	(chain F and resid 159:181)
91	X-RAY DIFFRACTION	91	(chain F and resid 182:213)
92	X-RAY DIFFRACTION	92	(chain F and resid 214:220)
93	X-RAY DIFFRACTION	93	(chain F and resid 221:255)
94	X-RAY DIFFRACTION	94	(chain F and resid 256:287)
95	X-RAY DIFFRACTION	95	(chain F and resid 288:305)
96	X-RAY DIFFRACTION	96	(chain F and resid 306:313)
97	X-RAY DIFFRACTION	97	(chain F and resid 314:355)
98	X-RAY DIFFRACTION	98	(chain F and resid 356:384)
99	X-RAY DIFFRACTION	99	(chain F and resid 385:396)
100	X-RAY DIFFRACTION	100	(chain F and resid 397:402)
101	X-RAY DIFFRACTION	101	(chain F and resid 403:440)
102	X-RAY DIFFRACTION	102	(chain F and resid 441:460)
103	X-RAY DIFFRACTION	103	(chain G and resid 3:8)
104	X-RAY DIFFRACTION	104	(chain G and resid 9:46)
105	X-RAY DIFFRACTION	105	(chain G and resid 47:83)
106	X-RAY DIFFRACTION	106	(chain G and resid 84:131)
107	X-RAY DIFFRACTION	107	(chain G and resid 132:215)
108	X-RAY DIFFRACTION	108	(chain G and resid 216:225)
109	X-RAY DIFFRACTION	109	(chain G and resid 226:243)
110	X-RAY DIFFRACTION	110	(chain G and resid 244:253)
111	X-RAY DIFFRACTION	111	(chain G and resid 276:281)
112	X-RAY DIFFRACTION	112	(chain G and resid 282:300)
113	X-RAY DIFFRACTION	113	(chain G and resid 301:322)
114	X-RAY DIFFRACTION	114	(chain G and resid 323:335)
115	X-RAY DIFFRACTION	115	(chain G and resid 336:349)
116	X-RAY DIFFRACTION	116	(chain G and resid 350:375)
117	X-RAY DIFFRACTION	117	(chain G and resid 376:399)
118	X-RAY DIFFRACTION	118	(chain G and resid 400:460)
119	X-RAY DIFFRACTION	119	(chain H and resid 3:56)
120	X-RAY DIFFRACTION	120	(chain H and resid 57:63)
121	X-RAY DIFFRACTION	121	(chain H and resid 64:101)
122	X-RAY DIFFRACTION	122	(chain H and resid 102:153)
123	X-RAY DIFFRACTION	123	(chain H and resid 154:212)
124	X-RAY DIFFRACTION	124	(chain H and resid 213:221)
125	X-RAY DIFFRACTION	125	(chain H and resid 222:241)
126	X-RAY DIFFRACTION	126	(chain H and resid 242:253)
127	X-RAY DIFFRACTION	127	(chain H and resid 254:275)
128	X-RAY DIFFRACTION	128	(chain H and resid 276:292)
129	X-RAY DIFFRACTION	129	(chain H and resid 293:309)
130	X-RAY DIFFRACTION	130	(chain H and resid 310:324)
131	X-RAY DIFFRACTION	131	(chain H and resid 325:332)
132	X-RAY DIFFRACTION	132	(chain H and resid 333:354)
133	X-RAY DIFFRACTION	133	(chain H and resid 355:401)
134	X-RAY DIFFRACTION	134	(chain H and resid 402:435)
135	X-RAY DIFFRACTION	135	(chain H and resid 436:460)