登録情報 | データベース: PDB / ID: 9gr8 |
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タイトル | Crystal structure of the N-terminal kinase domain from Saccharomyces cerevisiae Vip1 in complex with ADP. |
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要素 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase |
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キーワード | BIOSYNTHETIC PROTEIN / Inositol pyrophosphate / inositol pyrophosphate phosphatase / histidine acid phosphatase / phytase / enzyme mechanism / GAF domain / phosphate homeostasis |
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機能・相同性 | 機能・相同性情報
inositol hexakisphosphate 4-kinase activity / inositol hexakisphosphate 6-kinase activity / inositol hexakisphosphate 3-kinase activity / regulation of bipolar cell growth / inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity / Synthesis of pyrophosphates in the cytosol / diphosphoinositol pentakisphosphate kinase activity / diphosphoinositol-pentakisphosphate 1-kinase / 5-diphosphoinositol pentakisphosphate 1-kinase activity / inositol hexakisphosphate 1-kinase activity ...inositol hexakisphosphate 4-kinase activity / inositol hexakisphosphate 6-kinase activity / inositol hexakisphosphate 3-kinase activity / regulation of bipolar cell growth / inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity / Synthesis of pyrophosphates in the cytosol / diphosphoinositol pentakisphosphate kinase activity / diphosphoinositol-pentakisphosphate 1-kinase / 5-diphosphoinositol pentakisphosphate 1-kinase activity / inositol hexakisphosphate 1-kinase activity / inositol hexakisphosphate 5-kinase activity / inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity / inositol hexakisphosphate kinase activity / inositol phosphate biosynthetic process / inositol metabolic process / regulation of microtubule cytoskeleton organization / cytoskeleton / ATP binding / cytosol / cytoplasm類似検索 - 分子機能 Histidine acid phosphatase, VIP1 family / VIP1, N-terminal / Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain / ATP-grasp fold, RimK-type / RimK-like ATP-grasp domain / Histidine phosphatase superfamily, clade-2 / Histidine phosphatase superfamily (branch 2) / Histidine phosphatase superfamily類似検索 - ドメイン・相同性 ADENOSINE-5'-DIPHOSPHATE / Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase類似検索 - 構成要素 |
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生物種 |  Saccharomyces cerevisiae (パン酵母) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.18 Å |
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データ登録者 | Lee, K. / Raia, P. / Hothorn, M. |
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資金援助 | スイス, 米国, 2件 組織 | 認可番号 | 国 |
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Swiss National Science Foundation | CRSII5_209412 | スイス | Howard Hughes Medical Institute (HHMI) | 55008733 | 米国 |
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引用 | ジャーナル: Nat Commun / 年: 2025 タイトル: A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis. 著者: Raia, P. / Lee, K. / Bartsch, S.M. / Rico-Resendiz, F. / Portugal-Calisto, D. / Vadas, O. / Panse, V.G. / Fiedler, D. / Hothorn, M. |
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履歴 | 登録 | 2024年9月11日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2025年2月26日 | Provider: repository / タイプ: Initial release |
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