- PDB-8wu8: Crystal structure of the human RAD9-RAD1(F64A/M256A/F266A)-HUS1-R... -
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基本情報
登録情報
データベース: PDB / ID: 8wu8
タイトル
Crystal structure of the human RAD9-RAD1(F64A/M256A/F266A)-HUS1-RHINO(88-99) complex
要素
Cell cycle checkpoint control protein RAD9A
Cell cycle checkpoint protein RAD1
Checkpoint protein HUS1
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1
キーワード
CELL CYCLE / dna damage / checkpoint / dna repair / dna binding clamp
機能・相同性
機能・相同性情報
meiotic DNA integrity checkpoint signaling / checkpoint clamp complex / meiotic recombination checkpoint signaling / positive regulation of G0 to G1 transition / double-stranded DNA 3'-5' DNA exonuclease activity / exodeoxyribonuclease III / DNA replication checkpoint signaling / positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage / mitotic DNA replication checkpoint signaling / recombinational repair ...meiotic DNA integrity checkpoint signaling / checkpoint clamp complex / meiotic recombination checkpoint signaling / positive regulation of G0 to G1 transition / double-stranded DNA 3'-5' DNA exonuclease activity / exodeoxyribonuclease III / DNA replication checkpoint signaling / positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage / mitotic DNA replication checkpoint signaling / recombinational repair / mitotic intra-S DNA damage checkpoint signaling / embryo development ending in birth or egg hatching / HDR through Single Strand Annealing (SSA) / Impaired BRCA2 binding to RAD51 / Presynaptic phase of homologous DNA pairing and strand exchange / Activation of ATR in response to replication stress / response to UV / substantia nigra development / 3'-5' exonuclease activity / telomere maintenance / regulation of signal transduction by p53 class mediator / DNA damage checkpoint signaling / cellular response to ionizing radiation / nucleotide-excision repair / regulation of protein phosphorylation / double-strand break repair via homologous recombination / G2/M DNA damage checkpoint / histone deacetylase binding / SH3 domain binding / cellular response to UV / intrinsic apoptotic signaling pathway in response to DNA damage / chromosome / site of double-strand break / Processing of DNA double-strand break ends / DNA replication / Regulation of TP53 Activity through Phosphorylation / damaged DNA binding / cell cycle / intracellular membrane-bounded organelle / DNA repair / DNA damage response / nucleolus / protein kinase binding / enzyme binding / nucleoplasm / nucleus / cytoplasm / cytosol 類似検索 - 分子機能
Rad9, Rad1, Hus1-interacting nuclear orphan protein 1 / RAD9, RAD1, HUS1-interacting nuclear orphan protein / Cell cycle checkpoint protein, Rad1 / Cell cycle checkpoint, Hus1 / Rad9 / Rad9 / Checkpoint protein Hus1/Mec3 / Hus1-like protein / Rad1/Rec1/Rad17 / Rad9/Ddc1 ...Rad9, Rad1, Hus1-interacting nuclear orphan protein 1 / RAD9, RAD1, HUS1-interacting nuclear orphan protein / Cell cycle checkpoint protein, Rad1 / Cell cycle checkpoint, Hus1 / Rad9 / Rad9 / Checkpoint protein Hus1/Mec3 / Hus1-like protein / Rad1/Rec1/Rad17 / Rad9/Ddc1 / Repair protein Rad1/Rec1/Rad17 / : 類似検索 - ドメイン・相同性
Cell cycle checkpoint protein RAD1 / Checkpoint protein HUS1 / Cell cycle checkpoint control protein RAD9A / RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 類似検索 - 構成要素
A: Cell cycle checkpoint control protein RAD9A B: Checkpoint protein HUS1 C: Cell cycle checkpoint protein RAD1 D: RAD9, HUS1, RAD1-interacting nuclear orphan protein 1