登録情報 | データベース: PDB / ID: 8u85 |
---|
タイトル | Structural Basis of Human NOX5 Activation |
---|
要素 | - ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA
- NADPH oxidase 5
|
---|
キーワード | MEMBRANE PROTEIN / enzyme / oxidase / activation mechanism |
---|
機能・相同性 | 機能・相同性情報
regulation of fusion of sperm to egg plasma membrane / superoxide-generating NADPH oxidase activity / 酸化還元酵素; 酸素が電子受容体 / superoxide-generating NAD(P)H oxidase activity / cytoskeleton-dependent cytokinesis / NADPH oxidase complex / proton channel activity / superoxide anion generation / endothelial cell proliferation / Detoxification of Reactive Oxygen Species ...regulation of fusion of sperm to egg plasma membrane / superoxide-generating NADPH oxidase activity / 酸化還元酵素; 酸素が電子受容体 / superoxide-generating NAD(P)H oxidase activity / cytoskeleton-dependent cytokinesis / NADPH oxidase complex / proton channel activity / superoxide anion generation / endothelial cell proliferation / Detoxification of Reactive Oxygen Species / proton transmembrane transport / positive regulation of cytokine production / defense response / positive regulation of reactive oxygen species metabolic process / NADP binding / flavin adenine dinucleotide binding / angiogenesis / calcium ion binding / heme binding / endoplasmic reticulum membrane / apoptotic process / endoplasmic reticulum / plasma membrane類似検索 - 分子機能 : / Ferric reductase, NAD binding domain / Ferric reductase NAD binding domain / FAD-binding 8 / FAD-binding domain / Ferric reductase transmembrane component-like domain / Ferric reductase like transmembrane component / EF-hand domain / EF hand / FAD-binding domain, ferredoxin reductase-type ...: / Ferric reductase, NAD binding domain / Ferric reductase NAD binding domain / FAD-binding 8 / FAD-binding domain / Ferric reductase transmembrane component-like domain / Ferric reductase like transmembrane component / EF-hand domain / EF hand / FAD-binding domain, ferredoxin reductase-type / Ferredoxin-NADP reductase (FNR), nucleotide-binding domain / Ferredoxin reductase-type FAD binding domain profile. / Riboflavin synthase-like beta-barrel / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair類似検索 - ドメイン・相同性 FLAVIN-ADENINE DINUCLEOTIDE / HEME B/C / Chem-NDP / 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE / NADPH oxidase 5類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | 電子顕微鏡法 / 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.2 Å |
---|
データ登録者 | Cui, C. / Jiang, M. / Sun, J. |
---|
資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
---|
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | R01GM141357 | 米国 |
|
---|
引用 | ジャーナル: To Be Published タイトル: Structural Basis of Human NOX5 Activation 著者: Cui, C. / Jiang, M. / Sun, J. |
---|
履歴 | 登録 | 2023年9月15日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2024年5月1日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2024年5月8日 | Group: Database references / カテゴリ: citation_author / Item: _citation_author.name |
---|
|
---|