Entry | Database: PDB / ID: 8qn0 |
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Title | Soluble epoxide hydrolase in complex with RK3 |
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Components | Bifunctional epoxide hydrolase 2 |
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Keywords | HYDROLASE / COMPLEX / STRUCTURAL GENOMICS / STRUCTURAL GENOMICS CONSORTIUM / SGC |
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Function / homology | Function and homology information
lipid-phosphate phosphatase / 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity / stilbene catabolic process / Biosynthesis of maresins / phospholipid dephosphorylation / soluble epoxide hydrolase / lipid phosphatase activity / epoxide metabolic process / lysophosphatidic acid phosphatase activity / Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) ...lipid-phosphate phosphatase / 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity / stilbene catabolic process / Biosynthesis of maresins / phospholipid dephosphorylation / soluble epoxide hydrolase / lipid phosphatase activity / epoxide metabolic process / lysophosphatidic acid phosphatase activity / Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) / epoxide hydrolase activity / regulation of cholesterol metabolic process / phosphatase activity / peroxisomal matrix / toxic substance binding / dephosphorylation / cholesterol homeostasis / Peroxisomal protein import / response to toxic substance / peroxisome / positive regulation of gene expression / magnesium ion binding / protein homodimerization activity / extracellular exosome / cytosolSimilarity search - Function Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal / Phosphoglycolate phosphatase-like, domain 2 / HAD hydrolase, subfamily IA / Epoxide hydrolase-like / alpha/beta hydrolase fold / haloacid dehalogenase-like hydrolase / Alpha/beta hydrolase fold-1 / HAD superfamily / HAD-like superfamily / Alpha/Beta hydrolase foldSimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.49 Å |
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Authors | Kumar, A. / Zhu, F. / Ehrler, J.M.H. / Li, F. / Empel, C. / Xu, Y. / Atodiresei, I. / Koenigs, R.M. / Proschak, E. / Knapp, S. / Structural Genomics Consortium (SGC) |
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Funding support | Germany, 3items Organization | Grant number | Country |
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German Research Foundation (DFG) | 515365930 | Germany | German Research Foundation (DFG) | 448583558 | Germany | German Research Foundation (DFG) | 505561502 | Germany |
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Citation | Journal: Science / Year: 2024 Title: Photosensitization enables Pauson-Khand-type reactions with nitrenes. Authors: Li, F. / Zhu, W.F. / Empel, C. / Datsenko, O. / Kumar, A. / Xu, Y. / Ehrler, J.H.M. / Atodiresei, I. / Knapp, S. / Mykhailiuk, P.K. / Proschak, E. / Koenigs, R.M. |
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History | Deposition | Sep 25, 2023 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Feb 14, 2024 | Provider: repository / Type: Initial release |
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