positive regulation of chemokine (C-C motif) ligand 1 production / positive regulation of granulocyte colony-stimulating factor production / interleukin-7 receptor binding / interleukin-7-mediated signaling pathway / positive regulation of mast cell activation / positive regulation of receptor signaling pathway via STAT / positive regulation of cytokine-mediated signaling pathway / positive regulation of interleukin-13 production / positive regulation of interleukin-5 production / cell surface receptor signaling pathway via JAK-STAT ...positive regulation of chemokine (C-C motif) ligand 1 production / positive regulation of granulocyte colony-stimulating factor production / interleukin-7 receptor binding / interleukin-7-mediated signaling pathway / positive regulation of mast cell activation / positive regulation of receptor signaling pathway via STAT / positive regulation of cytokine-mediated signaling pathway / positive regulation of interleukin-13 production / positive regulation of interleukin-5 production / cell surface receptor signaling pathway via JAK-STAT / positive regulation of interleukin-10 production / defense response to fungus / positive regulation of chemokine production / positive regulation of tyrosine phosphorylation of STAT protein / Interleukin-7 signaling / cytokine activity / positive regulation of inflammatory response / antimicrobial humoral immune response mediated by antimicrobial peptide / positive regulation of interleukin-6 production / defense response to Gram-negative bacterium / positive regulation of cell population proliferation / negative regulation of apoptotic process / extracellular space / extracellular region 類似検索 - 分子機能
構造決定の手法: 分子置換 / 解像度: 1.65→40.97 Å / Cor.coef. Fo:Fc: 0.958 / Cor.coef. Fo:Fc free: 0.949 / SU B: 1.712 / SU ML: 0.058 / 交差検証法: THROUGHOUT / ESU R: 0.087 / ESU R Free: 0.086 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
反射数
%反射
Selection details
Rfree
0.20975
986
5.1 %
RANDOM
Rwork
0.18622
-
-
-
obs
0.18747
18527
99.08 %
-
溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: BABINET MODEL WITH MASK