positive regulation of chemokine (C-C motif) ligand 1 production / positive regulation of granulocyte colony-stimulating factor production / interleukin-7 receptor binding / interleukin-7-mediated signaling pathway / positive regulation of mast cell activation / positive regulation of receptor signaling pathway via STAT / positive regulation of cytokine-mediated signaling pathway / positive regulation of interleukin-13 production / positive regulation of interleukin-5 production / cell surface receptor signaling pathway via JAK-STAT ...positive regulation of chemokine (C-C motif) ligand 1 production / positive regulation of granulocyte colony-stimulating factor production / interleukin-7 receptor binding / interleukin-7-mediated signaling pathway / positive regulation of mast cell activation / positive regulation of receptor signaling pathway via STAT / positive regulation of cytokine-mediated signaling pathway / positive regulation of interleukin-13 production / positive regulation of interleukin-5 production / cell surface receptor signaling pathway via JAK-STAT / positive regulation of interleukin-10 production / defense response to fungus / positive regulation of tyrosine phosphorylation of STAT protein / positive regulation of chemokine production / Interleukin-7 signaling / cytokine activity / cytokine-mediated signaling pathway / positive regulation of interleukin-6 production / positive regulation of inflammatory response / antimicrobial humoral immune response mediated by antimicrobial peptide / defense response to Gram-negative bacterium / positive regulation of cell population proliferation / negative regulation of apoptotic process / extracellular space / extracellular region Similarity search - Function
Mass: 18.015 Da / Num. of mol.: 74 / Source method: isolated from a natural source / Formula: H2O
Has ligand of interest
Y
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Experimental details
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Experiment
Experiment
Method: X-RAY DIFFRACTION / Number of used crystals: 1
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Sample preparation
Crystal
Density Matthews: 2.72 Å3/Da / Density % sol: 54.76 %
Crystal grow
Temperature: 293 K / Method: vapor diffusion, hanging drop Details: 30% PEG MME 500/PEG 20000, 0.1 M Carboxylic acids mix and 0.1 M Buffer system 3 pH 8.5
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Data collection
Diffraction
Mean temperature: 100 K / Serial crystal experiment: N