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- PDB-8qfw: Murine pyridoxal phosphatase in complex with 7,8-dihydroxyflavone -
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Open data
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Basic information
Entry | Database: PDB / ID: 8qfw | ||||||
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Title | Murine pyridoxal phosphatase in complex with 7,8-dihydroxyflavone | ||||||
![]() | Chronophin | ||||||
![]() | HYDROLASE / Phosphatase / Inhibitor / Chronophin | ||||||
Function / homology | ![]() pyridoxal phosphatase / pyridoxal phosphate catabolic process / actin rod assembly / pyridoxal phosphatase activity / contractile ring / positive regulation of actin filament depolymerization / regulation of modification of postsynaptic structure / cellular response to ATP / regulation of mitotic nuclear division / myosin phosphatase activity ...pyridoxal phosphatase / pyridoxal phosphate catabolic process / actin rod assembly / pyridoxal phosphatase activity / contractile ring / positive regulation of actin filament depolymerization / regulation of modification of postsynaptic structure / cellular response to ATP / regulation of mitotic nuclear division / myosin phosphatase activity / protein-serine/threonine phosphatase / dephosphorylation / growth factor binding / phosphoprotein phosphatase activity / lamellipodium membrane / cleavage furrow / heat shock protein binding / protein dephosphorylation / regulation of cytokinesis / ruffle membrane / cell-cell junction / actin cytoskeleton / midbody / postsynapse / glutamatergic synapse / magnesium ion binding / protein homodimerization activity / cytosol / cytoplasm Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Schindelin, H. / Gohla, A. | ||||||
Funding support | ![]()
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![]() | ![]() Title: 7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase. Authors: Brenner, M. / Zink, C. / Witzinger, L. / Keller, A. / Hadamek, K. / Bothe, S. / Neuenschwander, M. / Villmann, C. / von Kries, J.P. / Schindelin, H. / Jeanclos, E. / Gohla, A. #1: ![]() Title: 7,8-Dihydroxyflavone is a direct inhibitor of pyridoxal phosphatase Authors: Brenner, M. / Zink, C. / Witzinger, L. / Keller, A. / Hadamek, K. / Bothe, S. / Neuenschwander, M. / Villmann, C. / von Kries, J.P. / Schindelin, H. / Jeanclos, E. / Gohla, A. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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PDBx/mmCIF format | ![]() | 419.6 KB | Display | ![]() |
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PDB format | ![]() | 291 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 8s8aC ![]() 9em1C C: citing same article ( |
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Similar structure data | Similarity search - Function & homology ![]() |
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Assembly
Deposited unit | ![]()
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: ens_1
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