- PDB-8gab: Crystal structure of CTLA-4 in complex with a high affinity CTLA-... -
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Basic information
Entry
Database: PDB / ID: 8gab
Title
Crystal structure of CTLA-4 in complex with a high affinity CTLA-4 binder
Components
CTLA-4 binder
Cytotoxic T-lymphocyte protein 4
Keywords
DE NOVO PROTEIN/Immune System / CTLA-4 / De novo protein design / high affinity binder / IMMUNE SYSTEM / DE NOVO PROTEIN-Immune System complex
Function / homology
Function and homology information
protein complex involved in cell adhesion / negative regulation of regulatory T cell differentiation / RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) / clathrin-coated endocytic vesicle / CTLA4 inhibitory signaling / negative regulation of B cell proliferation / negative regulation of T cell proliferation / B cell receptor signaling pathway / T cell receptor signaling pathway / adaptive immune response ...protein complex involved in cell adhesion / negative regulation of regulatory T cell differentiation / RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) / clathrin-coated endocytic vesicle / CTLA4 inhibitory signaling / negative regulation of B cell proliferation / negative regulation of T cell proliferation / B cell receptor signaling pathway / T cell receptor signaling pathway / adaptive immune response / immune response / positive regulation of apoptotic process / external side of plasma membrane / DNA damage response / perinuclear region of cytoplasm / Golgi apparatus / plasma membrane Similarity search - Function