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Yorodumi- PDB-8f8w: Crystal structure of Nb.X0 bound to the afucosylated human IgG1 f... -
+Open data
-Basic information
Entry | Database: PDB / ID: 8f8w | ||||||||||||
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Title | Crystal structure of Nb.X0 bound to the afucosylated human IgG1 fragment crystal form I | ||||||||||||
Components |
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Keywords | IMMUNE SYSTEM / nanobody / glycobiology / immunoglobulin | ||||||||||||
Function / homology | Function and homology information immunoglobulin complex, circulating / immunoglobulin receptor binding / complement activation, classical pathway / antigen binding / antibacterial humoral response / blood microparticle / extracellular exosome / metal ion binding / plasma membrane Similarity search - Function | ||||||||||||
Biological species | Homo sapiens (human) Camelidae mixed library (mammal) | ||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.71 Å | ||||||||||||
Authors | Goldgur, Y. / Ravetch, J. / Gupta, A. / Kao, K. / Oren, D. | ||||||||||||
Funding support | United States, 3items
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Citation | Journal: Nat Commun / Year: 2023 Title: Mechanism of glycoform specificity and in vivo protection by an anti-afucosylated IgG nanobody. Authors: Gupta, A. / Kao, K.S. / Yamin, R. / Oren, D.A. / Goldgur, Y. / Du, J. / Lollar, P. / Sundberg, E.J. / Ravetch, J.V. | ||||||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 8f8w.cif.gz | 655.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb8f8w.ent.gz | 457.9 KB | Display | PDB format |
PDBx/mmJSON format | 8f8w.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 8f8w_validation.pdf.gz | 1.9 MB | Display | wwPDB validaton report |
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Full document | 8f8w_full_validation.pdf.gz | 2 MB | Display | |
Data in XML | 8f8w_validation.xml.gz | 52.4 KB | Display | |
Data in CIF | 8f8w_validation.cif.gz | 71 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/f8/8f8w ftp://data.pdbj.org/pub/pdb/validation_reports/f8/8f8w | HTTPS FTP |
-Related structure data
Related structure data | 8f8vC 8f8xC C: citing same article (ref.) |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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