登録情報 | データベース: PDB / ID: 8eec |
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タイトル | Crystal structure of HPK1 citron-homology domain |
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要素 | Isoform 2 of Mitogen-activated protein kinase kinase kinase kinase 1 |
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キーワード | TRANSFERASE / beta-propeller / scaffolding |
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機能・相同性 | 機能・相同性情報
MAP kinase kinase kinase kinase activity / cellular response to phorbol 13-acetate 12-myristate / JNK cascade / peptidyl-serine phosphorylation / cell population proliferation / positive regulation of MAPK cascade / protein autophosphorylation / non-specific serine/threonine protein kinase / intracellular signal transduction / protein phosphorylation ...MAP kinase kinase kinase kinase activity / cellular response to phorbol 13-acetate 12-myristate / JNK cascade / peptidyl-serine phosphorylation / cell population proliferation / positive regulation of MAPK cascade / protein autophosphorylation / non-specific serine/threonine protein kinase / intracellular signal transduction / protein phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / ATP binding / membrane / cytoplasm類似検索 - 分子機能 Mitogen-activated protein (MAP) kinase kinase kinase kinase / Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2 / CNH domain / Citron homology (CNH) domain / Citron homology (CNH) domain profile. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. ...Mitogen-activated protein (MAP) kinase kinase kinase kinase / Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2 / CNH domain / Citron homology (CNH) domain / Citron homology (CNH) domain profile. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily類似検索 - ドメイン・相同性 PHOSPHATE ION / Mitogen-activated protein kinase kinase kinase kinase 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 単波長異常分散 / 解像度: 2.5 Å |
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データ登録者 | Wu, P. / Lehoux, I. / Wang, W. |
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資金援助 | 1件 |
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引用 | ジャーナル: To Be Published タイトル: HPK1 Citron Homology Domain Serves as a Scaffold to Promote Phosphorylation of SLP76 著者: Chitre, A. / Wu, P. / Walters, B. / Wang, X. / Du, X. / Lehoux, I. / Fong, R. / Arata, A. / Frnake, Y. / Grogan, J.L. / Mellman, I. / Camps-Agrar, L. / Wang, W. |
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履歴 | 登録 | 2022年9月6日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2024年3月27日 | Provider: repository / タイプ: Initial release |
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