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TitleHPK1 citron homology domain regulates phosphorylation of SLP76 and modulates kinase domain interaction dynamics
Journal, issue, pagesNat Commun, Vol. 15, Page 3725-, Year 2024
Publish dateSep 6, 2022 (structure data deposition date)
AuthorsChitre, A.S. / Wu, P. / Walters, B.T. / Wang, X. / Bouyssou, A. / Du, X. / Lehoux, I. / Fong, R. / Arata, A. / Chan, J. ...Chitre, A.S. / Wu, P. / Walters, B.T. / Wang, X. / Bouyssou, A. / Du, X. / Lehoux, I. / Fong, R. / Arata, A. / Chan, J. / Wang, D. / Franke, Y. / Grogan, J.L. / Mellman, I. / Comps-Agrar, L. / Wang, W.
External linksNat Commun / Search PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-8eec:
Crystal structure of HPK1 citron-homology domain
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / beta-propeller / scaffolding

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