登録情報 | データベース: PDB / ID: 8e1s |
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タイトル | Asp1 kinase in complex with ADPNP Mn IP6 |
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要素 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase |
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キーワード | TRANSFERASE / Inositol pyrophosphosphate IPP kinase Fission yeast |
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機能・相同性 | 機能・相同性情報
regulation of bipolar cell growth / inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity / inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity / regulation of mitotic spindle elongation (spindle phase three) / Synthesis of pyrophosphates in the cytosol / diphosphoinositol-pentakisphosphate 1-kinase / diphosphoinositol pentakisphosphate kinase activity / 5-diphosphoinositol pentakisphosphate 1-kinase activity / inositol hexakisphosphate 1-kinase activity / inositol hexakisphosphate 3-kinase activity ...regulation of bipolar cell growth / inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity / inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity / regulation of mitotic spindle elongation (spindle phase three) / Synthesis of pyrophosphates in the cytosol / diphosphoinositol-pentakisphosphate 1-kinase / diphosphoinositol pentakisphosphate kinase activity / 5-diphosphoinositol pentakisphosphate 1-kinase activity / inositol hexakisphosphate 1-kinase activity / inositol hexakisphosphate 3-kinase activity / inositol-1,3,4,5,6-pentakisphosphate kinase activity / inositol hexakisphosphate 5-kinase activity / inositol hexakisphosphate kinase activity / inositol phosphate catabolic process / inositol phosphate metabolic process / signaling / inositol phosphate biosynthetic process / intracellular phosphate ion homeostasis / inositol metabolic process / mitotic spindle assembly / regulation of microtubule cytoskeleton organization / 2 iron, 2 sulfur cluster binding / cytoskeleton / ATP hydrolysis activity / ATP binding / nucleus / cytosol類似検索 - 分子機能 Histidine acid phosphatase, VIP1 family / VIP1, N-terminal / Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain / ATP-grasp fold, RimK-type / RimK-like ATP-grasp domain / Histidine phosphatase superfamily, clade-2 / Histidine phosphatase superfamily (branch 2) / Histidine phosphatase superfamily類似検索 - ドメイン・相同性 PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / INOSITOL HEXAKISPHOSPHATE / : / Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase類似検索 - 構成要素 |
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生物種 | ![](img/tx_yeast.gif) Schizosaccharomyces pombe (分裂酵母) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.72 Å |
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データ登録者 | Goldgur, Y. / Shuman, S. / Benjamin, B. |
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資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | R35-GM126945 | 米国 |
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引用 | ジャーナル: Mbio / 年: 2022 タイトル: Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States. 著者: Benjamin, B. / Goldgur, Y. / Jork, N. / Jessen, H.J. / Schwer, B. / Shuman, S. |
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履歴 | 登録 | 2022年8月11日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2022年11月30日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2022年12月21日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.page_first / _citation.page_last ..._citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.name |
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改定 1.2 | 2023年1月4日 | Group: Database references / カテゴリ: citation / Item: _citation.journal_volume |
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改定 1.3 | 2023年10月25日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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