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基本情報
登録情報 | データベース: PDB / ID: 8dgz | ||||||
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タイトル | Caspase-7 bound to substrate mimic and allosteric inhibitor | ||||||
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![]() | APOPTOSIS/APOPTOSIS INHIBITOR / allostery / inhibitor / ternary / APOPTOSIS-APOPTOSIS INHIBITOR complex | ||||||
機能・相同性 | ![]() caspase-7 / lymphocyte apoptotic process / positive regulation of plasma membrane repair / cellular response to staurosporine / cysteine-type endopeptidase activity involved in execution phase of apoptosis / SMAC, XIAP-regulated apoptotic response / Activation of caspases through apoptosome-mediated cleavage / cysteine-type endopeptidase activity involved in apoptotic process / SMAC (DIABLO) binds to IAPs / SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ...caspase-7 / lymphocyte apoptotic process / positive regulation of plasma membrane repair / cellular response to staurosporine / cysteine-type endopeptidase activity involved in execution phase of apoptosis / SMAC, XIAP-regulated apoptotic response / Activation of caspases through apoptosome-mediated cleavage / cysteine-type endopeptidase activity involved in apoptotic process / SMAC (DIABLO) binds to IAPs / SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes / fibroblast apoptotic process / execution phase of apoptosis / Apoptotic cleavage of cellular proteins / protein maturation / Caspase-mediated cleavage of cytoskeletal proteins / response to UV / cysteine-type peptidase activity / striated muscle cell differentiation / protein catabolic process / protein processing / positive regulation of neuron apoptotic process / peptidase activity / heart development / cellular response to lipopolysaccharide / neuron apoptotic process / aspartic-type endopeptidase activity / defense response to bacterium / cysteine-type endopeptidase activity / apoptotic process / proteolysis / RNA binding / extracellular space / nucleoplasm / nucleus / cytoplasm / cytosol 類似検索 - 分子機能 | ||||||
生物種 | ![]() synthetic construct (人工物) | ||||||
手法 | ![]() ![]() ![]() | ||||||
![]() | Propp, J. / Kalenkiewicz, A. / Kathryn, F.H. / Spies, M.A. | ||||||
資金援助 | ![]()
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![]() | ![]() タイトル: Allosteric Tuning of Caspase-7: Establishing the Nexus of Structure and Catalytic Power. 著者: Hobbs, K.F. / Propp, J. / Vance, N.R. / Kalenkiewicz, A. / Witkin, K.R. / Ashley Spies, M. | ||||||
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構造の表示
構造ビューア | 分子: ![]() ![]() |
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その他 | ![]() |
-検証レポート
文書・要旨 | ![]() | 652.4 KB | 表示 | ![]() |
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文書・詳細版 | ![]() | 659 KB | 表示 | |
XML形式データ | ![]() | 18.2 KB | 表示 | |
CIF形式データ | ![]() | 24.2 KB | 表示 | |
アーカイブディレクトリ | ![]() ![]() | HTTPS FTP |
-関連構造データ
関連構造データ | ![]() 8dj3C ![]() 1f1jS S: 精密化の開始モデル C: 同じ文献を引用 ( |
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類似構造データ | 類似検索 - 機能・相同性 ![]() |
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集合体
登録構造単位 | ![]()
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非結晶学的対称性 (NCS) | NCSドメイン:
NCSドメイン領域: Ens-ID: 1
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