Entry Database : PDB / ID : 8cod Structure visualization Downloads & linksTitle Crystal structure of S-adenosyl-L-homocysteine hydrolase from Mus musculus in complex with inosine ComponentsAdenosylhomocysteinase Details Keywords HYDROLASE / Complex / S-adenosyl-L-homocysteine (SAH) / S-adenosyl-L-methionine (SAM)Function / homology Function and homology informationFunction Domain/homology Component
Sulfur amino acid metabolism / S-adenosylhomocysteine catabolic process / Methylation / adenyl nucleotide binding / circadian sleep/wake cycle / chronic inflammatory response to antigenic stimulus / adenosylhomocysteinase / adenosylhomocysteinase activity / S-adenosylmethionine cycle / response to nutrient ... Sulfur amino acid metabolism / S-adenosylhomocysteine catabolic process / Methylation / adenyl nucleotide binding / circadian sleep/wake cycle / chronic inflammatory response to antigenic stimulus / adenosylhomocysteinase / adenosylhomocysteinase activity / S-adenosylmethionine cycle / response to nutrient / NAD binding / melanosome / one-carbon metabolic process / copper ion binding / endoplasmic reticulum / identical protein binding / nucleus / cytosol Similarity search - Function Adenosylhomocysteinase-like / S-adenosyl-L-homocysteine hydrolase, conserved site / Adenosylhomocysteinase-like superfamily / S-adenosyl-L-homocysteine hydrolase, NAD binding domain / S-adenosyl-L-homocysteine hydrolase / S-adenosyl-L-homocysteine hydrolase signature 1. / S-adenosyl-L-homocysteine hydrolase signature 2. / S-adenosyl-L-homocysteine hydrolase / S-adenosyl-L-homocysteine hydrolase, NAD binding domain / S-adenosyl-L-homocysteine hydrolase, NAD binding domain / NAD(P)-binding domain superfamily Similarity search - Domain/homologyBiological species Mus musculus (house mouse)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.48 Å DetailsAuthors Saleem-Batcha, R. / Popadic, D. / Koeppl, L.H. / Andexer, J.N. Funding support Germany, European Union, 2items Details Hide detailsOrganization Grant number Country German Research Foundation (DFG) 235777276/RTG1976 Germany European Research Council (ERC) ERC project 716966 European Union
CitationJournal : To Be Published Title : Crystal structure of S-adenosyl-L-homocysteine hydrolase from Mus musculus in complex with inosineAuthors : Saleem-Batcha, R. / Popadic, D. / Koeppl, L.H. / Andexer, J.N. History Deposition Feb 27, 2023 Deposition site : PDBE / Processing site : PDBERevision 1.0 Mar 6, 2024 Provider : repository / Type : Initial release