SMODS-associated and fused to various effectors domain-containing protein
キーワード
HYDROLASE / Protease / CRISPR type III / cOA / cA4 / peptide binding protein
機能・相同性
SMODS-associated and fused to various effectors / SMODS-associated and fused to various effectors sensor domain / Ribosomal protein S5 domain 2-type fold, subgroup / Ribosomal protein S5 domain 2-type fold / membrane / : / TRIETHYLENE GLYCOL / RNA / SMODS-associated and fused to various effectors domain-containing protein
タイプ: Polycyclic / クラス: Antiviral / 分子量: 1271.866 Da / 分子数: 1 / 由来タイプ: 合成 詳細: Cyclic oligoadenylates such as c-tetraAMP were found to be novel bacterial second messengers. Antiviral in context of signalling for Type III CRISPR-Cas systems. 由来: (合成) Sulfurihydrogenibium (バクテリア) / 参照: BIRD: PRD_002431
Cyclic oligoadenylates such as c-tetraAMP were found to be novel bacterial second messengers. ...Cyclic oligoadenylates such as c-tetraAMP were found to be novel bacterial second messengers. CRISPR-Cas systems provide bacteria with adaptive immunity against bacteriophages. Cyclic oligoadenylate signaling was found to be essential for the type III system against the jumbo phage.
研究の焦点であるリガンドがあるか
N
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実験情報
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実験
実験
手法: X線回折 / 使用した結晶の数: 1
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試料調製
結晶
マシュー密度: 3.02 Å3/Da / 溶媒含有率: 59.31 %
結晶化
温度: 293 K / 手法: 蒸気拡散法, シッティングドロップ法 / 詳細: 0.1 M Tris-Cl pH 8.0, 38.8 % PEG 400, 0.29 M Li2SO4
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データ収集
回折
平均測定温度: 100 K / Serial crystal experiment: N
放射光源
由来: シンクロトロン / サイト: PETRA III, EMBL c/o DESY / ビームライン: P13 (MX1) / 波長: 0.97626 Å