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- PDB-8a0y: Crystal structure of mouse contactin 2 immunoglobulin domains -

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Basic information

Entry
Database: PDB / ID: 8a0y
TitleCrystal structure of mouse contactin 2 immunoglobulin domains
ComponentsContactin-2
KeywordsCELL ADHESION / cell adhesion molecule(s) / immunoglobulin / glycoprotein / myelin / juxtaparanodal / contactin / TAG-1 / axonin-1 / TAX-1 / horseshoe
Function / homology
Function and homology information


establishment of protein localization to juxtaparanode region of axon / presynaptic membrane organization / regulation of axon diameter / positive regulation of adenosine receptor signaling pathway / regulation of astrocyte differentiation / reduction of food intake in response to dietary excess / clustering of voltage-gated potassium channels / cell adhesion mediator activity / cerebral cortex GABAergic interneuron migration / protein localization to juxtaparanode region of axon ...establishment of protein localization to juxtaparanode region of axon / presynaptic membrane organization / regulation of axon diameter / positive regulation of adenosine receptor signaling pathway / regulation of astrocyte differentiation / reduction of food intake in response to dietary excess / clustering of voltage-gated potassium channels / cell adhesion mediator activity / cerebral cortex GABAergic interneuron migration / protein localization to juxtaparanode region of axon / central nervous system myelination / positive regulation of protein processing / G protein-coupled adenosine receptor signaling pathway / axon initial segment / juxtaparanode region of axon / node of Ranvier / axonal fasciculation / regulation of cell morphogenesis / central nervous system neuron differentiation / adult walking behavior / negative regulation of neuron differentiation / fat cell differentiation / response to dietary excess / regulation of neuronal synaptic plasticity / side of membrane / axon guidance / learning / establishment of localization in cell / protein processing / receptor internalization / microtubule cytoskeleton organization / neuron migration / neuron projection development / myelin sheath / carbohydrate binding / postsynaptic membrane / neuron projection / axon / neuronal cell body / cell surface
Similarity search - Function
: / Immunoglobulin domain / Immunoglobulin I-set / Immunoglobulin I-set domain / Fibronectin type III domain / Fibronectin type 3 domain / Immunoglobulin subtype 2 / Immunoglobulin C-2 Type / Fibronectin type-III domain profile. / Fibronectin type III ...: / Immunoglobulin domain / Immunoglobulin I-set / Immunoglobulin I-set domain / Fibronectin type III domain / Fibronectin type 3 domain / Immunoglobulin subtype 2 / Immunoglobulin C-2 Type / Fibronectin type-III domain profile. / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold
Similarity search - Domain/homology
Biological speciesMus musculus (house mouse)
MethodX-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.5 Å
AuthorsChataigner, L.M.P. / Janssen, B.J.C.
Funding supportEuropean Union, 1items
OrganizationGrant numberCountry
European Research Council (ERC)European Union
CitationJournal: Structure / Year: 2024
Title: Contactin 2 homophilic adhesion structure and conformational plasticity.
Authors: Chataigner, L.M.P. / Tharichen, L. / Beugelink, J.W. / Granneman, J.C.M. / Mokiem, N.J. / Snijder, J. / Forster, F. / Janssen, B.J.C.
History
DepositionMay 30, 2022Deposition site: PDBE / Processing site: PDBE
Revision 1.0Nov 1, 2023Provider: repository / Type: Initial release
Revision 1.1Dec 6, 2023Group: Database references / Category: citation
Item: _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title
Revision 1.2Jan 17, 2024Group: Database references / Category: citation
Item: _citation.journal_volume / _citation.page_first / _citation.year
Revision 1.3Nov 6, 2024Group: Structure summary / Category: pdbx_entry_details / pdbx_modification_feature / Item: _pdbx_entry_details.has_protein_modification

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

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Assembly

Deposited unit
A: Contactin-2
B: Contactin-2
C: Contactin-2
hetero molecules


Theoretical massNumber of molelcules
Total (without water)202,96722
Polymers193,6523
Non-polymers9,31619
Water00
1
A: Contactin-2
B: Contactin-2
hetero molecules


Theoretical massNumber of molelcules
Total (without water)135,50715
Polymers129,1012
Non-polymers6,40613
Water0
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
2
A: Contactin-2
C: Contactin-2
hetero molecules


Theoretical massNumber of molelcules
Total (without water)135,08314
Polymers129,1012
Non-polymers5,98112
Water0
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)131.930, 159.784, 227.886
Angle α, β, γ (deg.)90.000, 96.740, 90.000
Int Tables number5
Space group name H-MC121
Symmetry operation#1: x,y,z
#2: -x,y,-z
#3: x+1/2,y+1/2,z
#4: -x+1/2,y+1/2,-z
Noncrystallographic symmetry (NCS)NCS domain:
IDEns-IDDetails
11(chain A and (resid 35 through 608 or resid 609...
21(chain B and (resid 35 through 608 or resid 609...
31(chain C and (resid 35 through 608 or resid 609...

NCS domain segments:
Dom-IDComponent-IDEns-IDSelection detailsAuth asym-IDAuth seq-ID
111(chain A and (resid 35 through 608 or resid 609...A35 - 608
121(chain A and (resid 35 through 608 or resid 609...A609 - 611
131(chain A and (resid 35 through 608 or resid 609...A613 - 615
141(chain A and (resid 35 through 608 or resid 609...A617
151(chain A and (resid 35 through 608 or resid 609...A623
211(chain B and (resid 35 through 608 or resid 609...B35 - 608
221(chain B and (resid 35 through 608 or resid 609...B609 - 611
231(chain B and (resid 35 through 608 or resid 609...B613 - 615
241(chain B and (resid 35 through 608 or resid 609...B617
251(chain B and (resid 35 through 608 or resid 609...B623
311(chain C and (resid 35 through 608 or resid 609...C35 - 608
321(chain C and (resid 35 through 608 or resid 609...C609 - 611
331(chain C and (resid 35 through 608 or resid 609...C613 - 615
341(chain C and (resid 35 through 608 or resid 609...C617
351(chain C and (resid 35 through 608 or resid 609...C623

NCS oper:
IDCodeMatrixVector
1given(0.764360448589, -0.594075450074, -0.250654072882), (-0.549431242796, -0.803542825311, 0.229007068299), (-0.33745875907, -0.0373267666797, -0.940599967264)-15.9000975859, -87.9139842871, 58.2224572695
2given(0.196612186868, 0.97045919897, -0.139830580021), (0.970754629421, -0.212710282389, -0.111309412106), (-0.137764645073, -0.113856395957, -0.983899193854)-34.241181827, 62.3649049464, 140.294744738

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Components

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Protein , 1 types, 3 molecules ABC

#1: Protein Contactin-2 / Axonal glycoprotein TAG-1 / Axonin-1 / Transient axonal glycoprotein 1 / TAX-1


Mass: 64550.617 Da / Num. of mol.: 3
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Mus musculus (house mouse) / Gene: Cntn2, Tax / Production host: Homo sapiens (human) / References: UniProt: Q61330

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Sugars , 7 types, 19 molecules

#2: Polysaccharide alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1- ...alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 748.682 Da / Num. of mol.: 2
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DManpa1-3DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROHGlycam Condensed SequenceGMML 1.0
WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3/a4-b1_b4-c1_c3-d1WURCSPDB2Glycan 1.1.0
[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}}}}LINUCSPDB-CARE
#3: Polysaccharide beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta- ...beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 586.542 Da / Num. of mol.: 3
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROHGlycam Condensed SequenceGMML 1.0
WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5]/1-1-2/a4-b1_b4-c1WURCSPDB2Glycan 1.1.0
[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}}LINUCSPDB-CARE
#4: Polysaccharide alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D- ...alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 1072.964 Da / Num. of mol.: 1
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DManpa1-2DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROHGlycam Condensed SequenceGMML 1.0
WURCS=2.0/3,6,5/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3-3/a4-b1_b4-c1_c3-d1_c6-f1_d2-e1WURCSPDB2Glycan 1.1.0
[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{[(2+1)][a-D-Manp]{}}[(6+1)][a-D-Manp]{}}}}LINUCSPDB-CARE
#5: Polysaccharide 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 424.401 Da / Num. of mol.: 2
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DGlcpNAcb1-4DGlcpNAcb1-ROHGlycam Condensed SequenceGMML 1.0
WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1WURCSPDB2Glycan 1.1.0
[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}LINUCSPDB-CARE
#6: Polysaccharide alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2- ...alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 910.823 Da / Num. of mol.: 1 / Source method: obtained synthetically
DescriptorTypeProgram
DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROHGlycam Condensed SequenceGMML 1.0
WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3/a4-b1_b4-c1_c3-d1_c6-e1WURCSPDB2Glycan 1.1.0
[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}}LINUCSPDB-CARE
#7: Polysaccharide alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D- ...alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 1235.105 Da / Num. of mol.: 1
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DManpa1-3[DManpa1-6]DManpa1-6[DManpa1-3]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROHGlycam Condensed SequenceGMML 1.0
WURCS=2.0/3,7,6/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3-3-3/a4-b1_b4-c1_c3-d1_c6-e1_e3-f1_e6-g1WURCSPDB2Glycan 1.1.0
[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}}}LINUCSPDB-CARE
#8: Sugar
ChemComp-NAG / 2-acetamido-2-deoxy-beta-D-glucopyranose / N-acetyl-beta-D-glucosamine / 2-acetamido-2-deoxy-beta-D-glucose / 2-acetamido-2-deoxy-D-glucose / 2-acetamido-2-deoxy-glucose / N-ACETYL-D-GLUCOSAMINE


Type: D-saccharide, beta linking / Mass: 221.208 Da / Num. of mol.: 9 / Source method: obtained synthetically / Formula: C8H15NO6
IdentifierTypeProgram
DGlcpNAcbCONDENSED IUPAC CARBOHYDRATE SYMBOLGMML 1.0
N-acetyl-b-D-glucopyranosamineCOMMON NAMEGMML 1.0
b-D-GlcpNAcIUPAC CARBOHYDRATE SYMBOLPDB-CARE 1.0
GlcNAcSNFG CARBOHYDRATE SYMBOLGMML 1.0

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Details

Has ligand of interestN
Has protein modificationY

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Experimental details

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Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

CrystalDensity Matthews: 6.16 Å3/Da / Density % sol: 80.03 %
Crystal growTemperature: 269.15 K / Method: vapor diffusion, sitting drop / pH: 6
Details: 0.1 M Sodium malonate pH 6.0 and 12% w/v Polyethylene glycol 3,350

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Data collection

DiffractionMean temperature: 100 K / Serial crystal experiment: N
Diffraction sourceSource: SYNCHROTRON / Site: Diamond / Beamline: I03 / Wavelength: 0.9762 Å
DetectorType: DECTRIS EIGER2 XE 16M / Detector: PIXEL / Date: Jul 6, 2019
RadiationProtocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 0.9762 Å / Relative weight: 1
ReflectionResolution: 3.5→65 Å / Num. obs: 58926 / % possible obs: 99.3 % / Redundancy: 6 % / CC1/2: 0.974 / Rmerge(I) obs: 0.16 / Rpim(I) all: 0.071 / Rrim(I) all: 0.175 / Net I/σ(I): 4.6 / Num. measured all: 351683 / Scaling rejects: 526
Reflection shell

Diffraction-ID: 1

Resolution (Å)Redundancy (%)Rmerge(I) obsNum. measured allNum. unique obsCC1/2Rpim(I) allRrim(I) allNet I/σ(I) obs% possible all
3.5-3.596.12.5482763444980.2381.1312.7930.598.5
15.24-655.80.11842787390.9660.0560.13114.197.7

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Processing

Software
NameVersionClassification
PHENIX1.18.2_3874refinement
DIALSdata reduction
Aimlessdata scaling
PHASERphasing
RefinementMethod to determine structure: MOLECULAR REPLACEMENT
Starting model: 2OM5

2om5


Resolution: 3.5→59.82 Å / SU ML: 0.63 / Cross valid method: THROUGHOUT / σ(F): 1.34 / Phase error: 30.34 / Stereochemistry target values: ML
RfactorNum. reflection% reflection
Rfree0.2643 2977 5.07 %
Rwork0.225 55772 -
obs0.227 58749 99.2 %
Solvent computationShrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
Displacement parametersBiso max: 575.8 Å2 / Biso mean: 251.6085 Å2 / Biso min: 85.8 Å2
Refinement stepCycle: final / Resolution: 3.5→59.82 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms13275 0 615 0 13890
Biso mean--262.46 --
Num. residues----1722
Refine LS restraints NCS
Ens-IDDom-IDAuth asym-IDNumberRefine-IDRmsType
11A8118X-RAY DIFFRACTION12.179TORSIONAL
12B8118X-RAY DIFFRACTION12.179TORSIONAL
13C8118X-RAY DIFFRACTION12.179TORSIONAL
LS refinement shell

Refine-ID: X-RAY DIFFRACTION / Rfactor Rfree error: 0 / Total num. of bins used: 21

Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkNum. reflection all% reflection obs (%)
3.5-3.560.37871530.39822589274297
3.56-3.620.41431470.36542606275399
3.62-3.680.36641370.350927102847100
3.68-3.760.40741290.329126112740100
3.76-3.830.36831450.303726832828100
3.83-3.920.34221460.283826272773100
3.92-4.010.27911410.266427122853100
4.01-4.110.3211540.254126372791100
4.11-4.220.29521420.24672629277199
4.22-4.340.25831330.22782587272096
4.34-4.480.25581270.20382652277999
4.48-4.640.24781680.186526422810100
4.64-4.830.22811320.190726892821100
4.83-5.050.25251510.190426572808100
5.05-5.310.23131310.188626842815100
5.31-5.650.2451270.190126882815100
5.65-6.080.3281300.2052691282199
6.08-6.690.26361470.23442583273097
6.69-7.660.27941440.231826922836100
7.66-9.640.25281530.209426972850100
9.64-59.820.22811400.22332706284698
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
19.3842-1.16492.56517.09832.01654.01450.03450.8972-0.1544-0.26760.8376-1.3033-0.7296-0.2578-0.81311.62380.1906-0.25621.60060.14772.7816-44.4551-48.122824.4935
25.6942-2.35932.01268.7541-4.38949.48210.3679-0.78720.82592.20450.2055-0.55370.55440.311-0.5671.89160.1986-0.50171.5591-0.23242.5434-6.8578-47.690843.6883
38.95953.63274.50823.77131.48149.4037-0.39321.3595-1.50790.58541.0967-1.94050.38550.9676-0.98212.01080.2574-0.83051.3873-0.46122.4428-7.3332-68.961236.5066
46.0387-1.7329-0.24327.27536.76157.63560.0503-0.09650.85190.2975-0.11950.0346-0.4204-0.1803-0.04481.1860.0803-0.33411.17780.05632.1626-50.7536-71.318222.0835
58.9871-3.1461-2.37558.4016-2.21029.06160.3443-0.3115-0.0399-0.9510.2127-0.19591.1581-0.3473-0.58660.82040.089-0.22981.18220.31621.1582-90.0567-76.3894-0.5616
67.54011.33931.95321.872-2.45827.92750.12991.12330.9520.07310.112-0.60981.09570.89320.24741.81960.1081-0.90661.498-0.36032.0368-97.5583-97.6998-31.4716
78.0231-1.5844-1.49388.0911.31179.2830.12831.1996-1.61730.1903-1.93542.44641.2013-1.67061.98111.7629-0.01340.24711.511-0.21472.1577-63.526325.504599.6521
810.02797.10747.75678.78433.81229.82280.2993-1.12640.62750.91-0.26440.6523-0.19910.4312-0.17181.3216-0.14940.13371.5191-0.16361.7641-70.246660.6772121.9899
95.43321.83522.14527.79590.32281.13160.82991.13760.993-2.02350.4126-1.1312-0.35711.1340.85660.9025-0.63910.55971.8468-0.29951.7272-50.556665.7683112.2498
104.0611-3.2592-0.79635.9503-2.6758.47280.35330.4620.0220.22610.6791-1.87871.88521.9944-0.41861.27430.6018-0.0832.05550.02121.3136-39.450724.925596.7024
111.7093-2.87691.40587.97320.25125.097-1.1139-0.7409-1.08561.51671.71161.12230.65441.61984.07451.90090.7318-0.22472.2422-0.44660.3507-17.90041.357369.6981
124.8353-3.8549-6.87434.55275.91199.31130.9775-1.36432.6919-0.7017-1.8013-1.3415-2.2219-1.54451.31143.6331-0.63320.03332.828-0.5084.2452-1.851424.816745.2823
137.6148-5.9922-7.58615.40995.53918.7205-1.517-0.7086-2.20320.3422-0.52792.21521.1779-2.0283-2.04010.94440.1895-0.67362.0307-0.78632.3041-36.1437-15.815148.2502
147.1279-0.87150.9084.27340.60654.15820.11852.09570.0409-1.5630.0149-0.1077-1.6837-0.22210.28631.36590.3052-0.58990.5236-0.29291.1252-6.7615-32.367223.394
154.0077-4.2705-4.6964.53684.17687.22490.7053-1.78380.54941.49380.1224-0.6879-1.88010.9596-0.81052.1729-0.64810.27591.6579-0.10722.0743.5573-13.17229.1692
164.4115-3.2099-1.42068.99071.0570.46270.58081.121.1598-2.863-0.4075-1.0053-0.8812-1.5017-0.97493.47611.1709-0.6181.9767-0.27631.7856-31.22828.21747.8235
176.7635-0.73883.93080.8176-1.75795.1751.42740.7404-1.5667-1.8776-1.22361.0517-0.4473-0.3939-0.45392.58010.6837-0.23331.7401-0.36990.5677-46.277337.087473.9571
180.49230.0743-0.39686.12642.97561.8187-0.7065-0.9399-1.4392.25070.7283-3.24830.90872.5010.08292.0429-0.52840.41343.5027-0.4883.5971-17.234250.585694.0206
Refinement TLS group
IDRefine-IDRefine TLS-IDSelection detailsAuth asym-IDAuth seq-ID
1X-RAY DIFFRACTION1(chain 'B' and ((resid 35 through 131) or (resid 609-612)))B0
2X-RAY DIFFRACTION2(chain 'B' and ((resid 132 through 235) or (resid 613-615)))B0
3X-RAY DIFFRACTION3(chain 'B' and resid 236 through 325)B236 - 325
4X-RAY DIFFRACTION4(chain 'B' and resid 326 through 416)B326 - 416
5X-RAY DIFFRACTION5(chain 'B' and ((resid 417 through 508) or (resid 616-624)))B0
6X-RAY DIFFRACTION6(chain 'B' and ((resid 509 through 608) or (resid 625)))B0
7X-RAY DIFFRACTION7(chain 'C' and ((resid 35 through 131) or (resid 609-611)))C0
8X-RAY DIFFRACTION8(chain 'C' and ((resid 132 through 235) or (resid 612-614)))C0
9X-RAY DIFFRACTION9(chain 'C' and resid 236 through 325)C236 - 325
10X-RAY DIFFRACTION10(chain 'C' and resid 326 through 416)C326 - 416
11X-RAY DIFFRACTION11(chain 'C' and ((resid 417 through 508) or (resid 615-623)))C0
12X-RAY DIFFRACTION12(chain 'C' and resid 509 through 608)C509 - 608
13X-RAY DIFFRACTION13(chain 'A' and ((resid 35 through 131) or (resid 609-612)))A0
14X-RAY DIFFRACTION14(chain 'A' and ((resid 132 through 235) or (resid 613-616)))A0
15X-RAY DIFFRACTION15(chain 'A' and resid 236 through 325)A236 - 325
16X-RAY DIFFRACTION16(chain 'A' and resid 326 through 416)A326 - 416
17X-RAY DIFFRACTION17(chain 'A' and ((resid 417 through 508) or (resid 617-624)))A0
18X-RAY DIFFRACTION18(chain 'A' and resid 509 through 608)A509 - 608

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