+Open data
-Basic information
Entry | Database: PDB / ID: 7uvs | |||||||||||||||
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Title | Pfs230 domain 1 bound by LMIV230-02 Fab | |||||||||||||||
Components |
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Keywords | CELL INVASION/IMMUNE SYSTEM / Antibody-fragment / malaria transmission / CELL INVASION / CELL INVASION-IMMUNE SYSTEM complex | |||||||||||||||
Function / homology | 6-Cysteine (6-Cys) domain / 6-Cysteine (6-Cys) domain superfamily / Sexual stage antigen s48/45 domain / 6-Cysteine (6-Cys) domain profile. / Sexual stage antigen s48/45 domain / cell surface / plasma membrane / Gametocyte surface protein P230 Function and homology information | |||||||||||||||
Biological species | Homo sapiens (human) Plasmodium falciparum (malaria parasite P. falciparum) | |||||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.06 Å | |||||||||||||||
Authors | Ivanochko, D. / Julien, J.P. | |||||||||||||||
Funding support | Canada, United States, 4items
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Citation | Journal: Immunity / Year: 2023 Title: Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230. Authors: Ivanochko, D. / Fabra-Garcia, A. / Teelen, K. / van de Vegte-Bolmer, M. / van Gemert, G.J. / Newton, J. / Semesi, A. / de Bruijni, M. / Bolscher, J. / Ramjith, J. / Szabat, M. / Vogt, S. / ...Authors: Ivanochko, D. / Fabra-Garcia, A. / Teelen, K. / van de Vegte-Bolmer, M. / van Gemert, G.J. / Newton, J. / Semesi, A. / de Bruijni, M. / Bolscher, J. / Ramjith, J. / Szabat, M. / Vogt, S. / Kraft, L. / Duncan, S. / Lee, S.M. / Kamya, M.R. / Feeney, M.E. / Jagannathan, P. / Greenhouse, B. / Sauerwein, R.W. / Richter King, C. / MacGill, R.S. / Bousema, T. / Jore, M.M. / Julien, J.P. | |||||||||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7uvs.cif.gz | 565.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7uvs.ent.gz | 412.1 KB | Display | PDB format |
PDBx/mmJSON format | 7uvs.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7uvs_validation.pdf.gz | 466.5 KB | Display | wwPDB validaton report |
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Full document | 7uvs_full_validation.pdf.gz | 477.4 KB | Display | |
Data in XML | 7uvs_validation.xml.gz | 49.8 KB | Display | |
Data in CIF | 7uvs_validation.cif.gz | 72.3 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/uv/7uvs ftp://data.pdbj.org/pub/pdb/validation_reports/uv/7uvs | HTTPS FTP |
-Related structure data
Related structure data | 7uvhC 7uviC 7uvoC 7uvqC 6ohgS C: citing same article (ref.) S: Starting model for refinement |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
Deposited unit |
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2 |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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