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Open data
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Basic information
Entry | Database: PDB / ID: 7u8u | ||||||
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Title | hTRAP1 with inhibitors | ||||||
![]() | Heat shock protein 75 kDa, mitochondrial | ||||||
![]() | CHAPERONE / hTRAP1 / inhibitor | ||||||
Function / homology | ![]() translational attenuation / negative regulation of cellular respiration / Respiratory electron transport / tumor necrosis factor receptor binding / negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide / chaperone-mediated protein folding / negative regulation of reactive oxygen species biosynthetic process / cell periphery / ATP-dependent protein folding chaperone / mitochondrial intermembrane space ...translational attenuation / negative regulation of cellular respiration / Respiratory electron transport / tumor necrosis factor receptor binding / negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide / chaperone-mediated protein folding / negative regulation of reactive oxygen species biosynthetic process / cell periphery / ATP-dependent protein folding chaperone / mitochondrial intermembrane space / unfolded protein binding / protein folding / mitochondrial inner membrane / mitochondrial matrix / protein kinase binding / ATP hydrolysis activity / mitochondrion / RNA binding / nucleoplasm / ATP binding / membrane Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Deng, J. / Matts, R. / Peng, S. | ||||||
Funding support | ![]()
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![]() | ![]() Title: Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes. Authors: Merfeld, T. / Peng, S. / Keegan, B.M. / Crowley, V.M. / Brackett, C.M. / Gutierrez, A. / McCann, N.R. / Reynolds, T.S. / Rhodes, M.C. / Byrd, K.M. / Deng, J. / Matts, R.L. / Blagg, B.S.J. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 364 KB | Display | ![]() |
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PDB format | ![]() | 298.2 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 929.3 KB | Display | ![]() |
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Full document | ![]() | 954.4 KB | Display | |
Data in XML | ![]() | 34.4 KB | Display | |
Data in CIF | ![]() | 46.1 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 7u8vC ![]() 7u8wC ![]() 7u8xC ![]() 5hphS S: Starting model for refinement C: citing same article ( |
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Similar structure data | Similarity search - Function & homology ![]() |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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