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Yorodumi- PDB-7sok: Structure of Nicotinamide N-Methyltransferase (NNMT) in complex w... -
+Open data
-Basic information
Entry | Database: PDB / ID: 7sok | ||||||||||||||||||
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Title | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor II329 | ||||||||||||||||||
Components | NNMT protein | ||||||||||||||||||
Keywords | TRANSFERASE/INHIBITOR / NNMT1 / inhibitor / methylation / TRANSFERASE-INHIBITOR complex | ||||||||||||||||||
Function / homology | Function and homology information nicotinamide metabolic process / nicotinamide N-methyltransferase activity / positive regulation of protein deacetylation / animal organ regeneration / positive regulation of gluconeogenesis / : / methylation / response to xenobiotic stimulus / cytosol Similarity search - Function | ||||||||||||||||||
Biological species | Homo sapiens (human) | ||||||||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.08 Å | ||||||||||||||||||
Authors | Yadav, R. / Iyamu, I.D. / Huang, R. / Noinaj, N. | ||||||||||||||||||
Funding support | United States, 5items
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Citation | Journal: To Be Published Title: Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor II329 Authors: Iyamu, I. / Vilseck, J.Z. / Yadav, R. / Noinaj, N. / Huang, R. | ||||||||||||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7sok.cif.gz | 222.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7sok.ent.gz | 176.1 KB | Display | PDB format |
PDBx/mmJSON format | 7sok.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7sok_validation.pdf.gz | 1.6 MB | Display | wwPDB validaton report |
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Full document | 7sok_full_validation.pdf.gz | 1.6 MB | Display | |
Data in XML | 7sok_validation.xml.gz | 44.3 KB | Display | |
Data in CIF | 7sok_validation.cif.gz | 58.7 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/so/7sok ftp://data.pdbj.org/pub/pdb/validation_reports/so/7sok | HTTPS FTP |
-Related structure data
Related structure data | 6pvsS S: Starting model for refinement |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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