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データを開く
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基本情報
登録情報 | データベース: PDB / ID: 7rtg | ||||||
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タイトル | Crystal Structure of the Human Adenosine Deaminase 1 | ||||||
![]() | Adenosine deaminase | ||||||
![]() | HYDROLASE / adenosine deaminase / zinc binding enzyme / holoenzyme | ||||||
機能・相同性 | ![]() purine nucleotide salvage / Defective ADA disrupts (deoxy)adenosine deamination / mature B cell apoptotic process / xanthine biosynthetic process / negative regulation of penile erection / negative regulation of mucus secretion / penile erection / positive regulation of germinal center formation / negative regulation of adenosine receptor signaling pathway / cytoplasmic vesicle lumen ...purine nucleotide salvage / Defective ADA disrupts (deoxy)adenosine deamination / mature B cell apoptotic process / xanthine biosynthetic process / negative regulation of penile erection / negative regulation of mucus secretion / penile erection / positive regulation of germinal center formation / negative regulation of adenosine receptor signaling pathway / cytoplasmic vesicle lumen / 2'-deoxyadenosine deaminase activity / inosine biosynthetic process / amide catabolic process / adenosine deaminase / germinal center B cell differentiation / purine-containing compound salvage / deaminase activity / adenosine catabolic process / adenosine deaminase activity / hypoxanthine salvage / deoxyadenosine catabolic process / dAMP catabolic process / adenosine metabolic process / positive regulation of T cell differentiation in thymus / AMP catabolic process / dATP catabolic process / mucus secretion / Ribavirin ADME / negative regulation of leukocyte migration / regulation of cell-cell adhesion mediated by integrin / response to purine-containing compound / embryonic digestive tract development / allantoin metabolic process / trophectodermal cell differentiation / Purine salvage / GMP salvage / positive regulation of smooth muscle contraction / Peyer's patch development / germinal center formation / negative regulation of mature B cell apoptotic process / AMP salvage / negative regulation of thymocyte apoptotic process / anchoring junction / positive regulation of alpha-beta T cell differentiation / alpha-beta T cell differentiation / positive regulation of heart rate / leukocyte migration / lung alveolus development / positive regulation of T cell receptor signaling pathway / thymocyte apoptotic process / B cell proliferation / smooth muscle contraction / : / positive regulation of calcium-mediated signaling / positive regulation of B cell proliferation / T cell activation / xenobiotic metabolic process / liver development / calcium-mediated signaling / placenta development / negative regulation of inflammatory response / T cell receptor signaling pathway / T cell differentiation in thymus / lysosome / cell adhesion / response to hypoxia / external side of plasma membrane / cell surface / zinc ion binding / membrane / plasma membrane / cytosol 類似検索 - 分子機能 | ||||||
生物種 | ![]() | ||||||
手法 | ![]() ![]() ![]() | ||||||
![]() | Ma, M.T. / Lieberman, R.L. / Blazeck, J. / Jennings, M.R. | ||||||
資金援助 | ![]()
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![]() | ![]() タイトル: Catalytically active holo Homo sapiens adenosine deaminase I adopts a closed conformation. 著者: Ma, M.T. / Jennings, M.R. / Blazeck, J. / Lieberman, R.L. | ||||||
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構造の表示
構造ビューア | 分子: ![]() ![]() |
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-関連構造データ
関連構造データ | ![]() 3iarS S: 精密化の開始モデル |
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集合体
登録構造単位 | ![]()
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単位格子 |
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Components on special symmetry positions |
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非結晶学的対称性 (NCS) | NCSドメイン:
NCSドメイン領域: Ens-ID: 1
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