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- PDB-7r7p: Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inosito... -
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Open data
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Basic information
Entry | Database: PDB / ID: 7r7p | ||||||||||||||||||||||||
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Title | Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6) | ||||||||||||||||||||||||
![]() | Gag polyprotein | ||||||||||||||||||||||||
![]() | PROTEIN BINDING / HIV-1 capsid / maturation inhibitors / HIV-AIDS | ||||||||||||||||||||||||
Function / homology | ![]() viral budding via host ESCRT complex / viral nucleocapsid / host cell cytoplasm / host cell nucleus / structural molecule activity / virion membrane / RNA binding / zinc ion binding / cytoplasm Similarity search - Function | ||||||||||||||||||||||||
Biological species | ![]() ![]() | ||||||||||||||||||||||||
Method | SOLID-STATE NMR / simulated annealing | ||||||||||||||||||||||||
![]() | Sarkar, S. / Zadrozny, K.K. / Zadorozhnyi, R. / Russell, R.W. / Quinn, C.M. / Kleinpeter, A. / Ablan, S. / Meshkin, H. / Perilla, J.R. / Ganser-Pornillos, B.K. ...Sarkar, S. / Zadrozny, K.K. / Zadorozhnyi, R. / Russell, R.W. / Quinn, C.M. / Kleinpeter, A. / Ablan, S. / Meshkin, H. / Perilla, J.R. / Ganser-Pornillos, B.K. / Pornillos, O. / Freed, E.O. / Gronenborn, A.M. / Polenova, T. | ||||||||||||||||||||||||
Funding support | ![]()
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![]() | ![]() Title: Structural basis of HIV-1 maturation inhibitor binding and activity. Authors: Sarkar, S. / Zadrozny, K.K. / Zadorozhnyi, R. / Russell, R.W. / Quinn, C.M. / Kleinpeter, A. / Ablan, S. / Meshkin, H. / Perilla, J.R. / Freed, E.O. / Ganser-Pornillos, B.K. / Pornillos, O. ...Authors: Sarkar, S. / Zadrozny, K.K. / Zadorozhnyi, R. / Russell, R.W. / Quinn, C.M. / Kleinpeter, A. / Ablan, S. / Meshkin, H. / Perilla, J.R. / Freed, E.O. / Ganser-Pornillos, B.K. / Pornillos, O. / Gronenborn, A.M. / Polenova, T. | ||||||||||||||||||||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 920 KB | Display | ![]() |
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PDB format | ![]() | 777.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 660.7 KB | Display | ![]() |
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Full document | ![]() | 883 KB | Display | |
Data in XML | ![]() | 79 KB | Display | |
Data in CIF | ![]() | 111.6 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 7r7qC C: citing same article ( |
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Similar structure data | Similarity search - Function & homology ![]() |
Other databases |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein | Mass: 11094.672 Da / Num. of mol.: 6 / Mutation: P241T Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() #2: Chemical | ChemComp-IHP / | #3: Chemical | ChemComp-2I4 / | Has ligand of interest | Y | |
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-Experimental details
-Experiment
Experiment | Method: SOLID-STATE NMR | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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NMR experiment |
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