+Open data
-Basic information
Entry | Database: PDB / ID: 7qem | |||||||||||||||
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Title | bacterial IMPDH chimera | |||||||||||||||
Components | Inosine-5'-monophosphate dehydrogenase | |||||||||||||||
Keywords | OXIDOREDUCTASE / Nucleotide synthesis | |||||||||||||||
Function / homology | Function and homology information C-rich single-stranded DNA binding / IMP dehydrogenase activity / IMP dehydrogenase / GMP biosynthetic process / GTP biosynthetic process / guanosine tetraphosphate binding / response to UV / single-stranded DNA binding / protein homotetramerization / protein-containing complex ...C-rich single-stranded DNA binding / IMP dehydrogenase activity / IMP dehydrogenase / GMP biosynthetic process / GTP biosynthetic process / guanosine tetraphosphate binding / response to UV / single-stranded DNA binding / protein homotetramerization / protein-containing complex / ATP binding / identical protein binding / metal ion binding / cytoplasm / cytosol Similarity search - Function | |||||||||||||||
Biological species | Escherichia coli (E. coli) Pseudomonas aeruginosa PAO1 (bacteria) | |||||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.09 Å | |||||||||||||||
Authors | Labesse, G. / Gelin, M. / Gedeon, A. / Haouz, A. / Munier-Lehmann, H. | |||||||||||||||
Funding support | France, 4items
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Citation | Journal: Protein Sci. / Year: 2023 Title: Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases. Authors: Gedeon, A. / Ayoub, N. / Brule, S. / Raynal, B. / Karimova, G. / Gelin, M. / Mechaly, A. / Haouz, A. / Labesse, G. / Munier-Lehmann, H. #1: Journal: Structure / Year: 2013 Title: MgATP regulates allostery and fiber formation in IMPDHs. Authors: Labesse, G. / Alexandre, T. / Vaupre, L. / Salard-Arnaud, I. / Him, J.L. / Raynal, B. / Bron, P. / Munier-Lehmann, H. | |||||||||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7qem.cif.gz | 740 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7qem.ent.gz | 513.5 KB | Display | PDB format |
PDBx/mmJSON format | 7qem.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7qem_validation.pdf.gz | 1.5 MB | Display | wwPDB validaton report |
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Full document | 7qem_full_validation.pdf.gz | 1.5 MB | Display | |
Data in XML | 7qem_validation.xml.gz | 57.5 KB | Display | |
Data in CIF | 7qem_validation.cif.gz | 78.4 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/qe/7qem ftp://data.pdbj.org/pub/pdb/validation_reports/qe/7qem | HTTPS FTP |
-Related structure data
Related structure data | 7qbjC 7qdxC 4dqwS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: ens_1
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