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Yorodumi- PDB-7pd6: Crystal structure of Lymnaea stagnalis Acetylcholine-binding prot... -
+Open data
-Basic information
Entry | Database: PDB / ID: 7pd6 | ||||||
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Title | Crystal structure of Lymnaea stagnalis Acetylcholine-binding protein (Ls-AChBP) Q55R/M114V double mutant complexed with Sulfoxaflor | ||||||
Components | Acetylcholine-binding protein | ||||||
Keywords | CHOLINE-BINDING PROTEIN / acetylcholine / protein / mutant / SIGNALING PROTEIN | ||||||
Function / homology | Function and homology information excitatory extracellular ligand-gated monoatomic ion channel activity / synaptic cleft / transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential / transmembrane signaling receptor activity / postsynapse / neuron projection / membrane Similarity search - Function | ||||||
Biological species | Lymnaea stagnalis (great pond snail) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2 Å | ||||||
Authors | Montgomery, M.G. | ||||||
Funding support | United Kingdom, 1items
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Citation | Journal: J.Med.Chem. / Year: 2022 Title: Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators. Authors: Montgomery, M. / Rendine, S. / Zimmer, C.T. / Elias, J. / Schaetzer, J. / Pitterna, T. / Benfatti, F. / Skaljac, M. / Bigot, A. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7pd6.cif.gz | 751.8 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7pd6.ent.gz | Display | PDB format | |
PDBx/mmJSON format | 7pd6.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7pd6_validation.pdf.gz | 2.8 MB | Display | wwPDB validaton report |
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Full document | 7pd6_full_validation.pdf.gz | 2.8 MB | Display | |
Data in XML | 7pd6_validation.xml.gz | 70 KB | Display | |
Data in CIF | 7pd6_validation.cif.gz | 94.8 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/pd/7pd6 ftp://data.pdbj.org/pub/pdb/validation_reports/pd/7pd6 | HTTPS FTP |
-Related structure data
Related structure data | 7pdbC 7pdrC 7pe5C 7pe6C 1uv6S S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
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